Lipids & Polymers

Lipoamide-PEG-Mal, MW 1,000 is a lipoic acid PEG derivative for surface modification of metallic particles/film. The maleimide moiety can react with cysteine or thiol molecule to form a thioether linkage. PEG chain linked to lipoic acid offers good water solubility, flexible linker structure, and enhanced biocompatibility. Reagent grade, for research purpose.

Lipoamide-PEG-Mal, MW 2,000 is a surface-active PEG derivative. Lipoic acid is a good metal chelator for many biomedical applications, such lipoic acid modified gold nanoparticles (AuNP) for therapeutics. The maleimide moiety can react with cysteine or thiol molecule to form a thioether linkage. Reagent grade, for research purpose.

Lipoamide-PEG-Mal, MW 3,400 is a maleimide polyPEG to form a thoether bond when reacted with thiol or cysteine. The polymer is also surface active which can bind to metal surface through disulfide (SS-) bond. Reagent grade, for research purpose.

Lipoamide-PEG-Mal, MW 5,000 is a lipoic acid polymer with flexible PEG chain to enhance biocompatibility and water solubility. It is used for surface modification or grafting of metal nanoparticles. The maleimide is reactive with thiol or cysteine at pH 6.5-7.5 to form a covalent thioether bond. Reagent grade, for research purpose.

Mal-PEG-CH2CO2H, MW 2,000 is a heterobifunctional polydisperse PEG which can react with thiol to form a thioether bond. The carboxylic acid is reactive with amine in the presenc of HATU or EDC via condensation reaction. Reagent grade, for research purpose.

Mal-PEG-CH2CO2H, MW 5,000 can react with thiol through condensation reaction to generate thiosuccinimide compound. The carboxylic acid (-COOH) is reactive with amine in the presence of activator, such as HATU or EDC, to form a stable amide bond. Reagent grade, for research purpose.

Fluorescein-PEG-Mal, MW 1,000 is a linear polyPEG with fluorescent probe (green) for labeling. The maleimide can react with thiol or cysteine via condensation reaction generating a thiosuccinimide bond. Reagent grade, for research purpose.

Rhodamine-PEG-Mal, MW 5,000 is a red fluorescent containing PEG polymer with terminal maleimide. Michael-addition of a thiol to a maleimide via condensation reaction is commonly used for bioconjugation of drugs to macromolecules. Reagent grade, for research purpose.

Stearic acid-PEG-Mal, MW 1,000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The terminal maleimide can react with thiol/cysteine via condensation reaction to form a stable thioether bond. Reagent grade, for research purpose.