Lipids & Polymers

Stearic acid-PEG-Mal, MW 2,000 is a heterobifunctional polyPEG with 18-carbon aliphatic chain and maleimide. The polymer has stearic acid as the hydrophobic tail and PEG as the hydrophilic chain, therefore it forms micelles in water. Maleimide can react with thiol or cysteine to generate thiosuccinimide molecule which is commonly used for bioconjugation. Reagent grade, for research purpose.

Stearic acid-PEG-Mal, MW 3,400 is a lipophilic thiol-reactive PEG polymer. The stearic acid can be used to encapsulate hydrophobic therapeutic agents while the PEG chain increases overall water solubility and biocompatibilty. Reaction between maleimide and thiol generates thioether linkage. Reagent grade, for research purpose.

Stearic acid-PEG-Mal, MW 5,000 is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal maleimide can react with thiol/cysteine via Michael-addition to form a thiosuccinimide molecule. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research purpose.

Fmoc-NH-PEG-OH, MW 5,000 is a hydroxy polyPEG with Fmoc protected amine. The hydroxy end group can further derivatize the compound. The Fmoc protecting group can be removed under basic condition. Reagent grade, for research purpose.

t-Boc-N-amido-PEG-OH, MW 1,000 is a linear heterofunctional polyPEG with protected amine and terminal hydroxyl. The hydroxyl can further derivatize to other compound. The protected amine can be regenerated under acidic condition to produce a free amine. Reagent grade, for research purpose.

t-Boc-N-amido-PEG-OH, MW 2,000 is a t-boc protected PEG reagent. The t-boc protecting group can be removed using HCl or TFA to generate a free amine which can then react with an NHS ester or carboxyl in the presence of activator, such as HATU or EDC. Reagent grade, for research purpose.

t-Boc-N-amido-PEG-OH, MW 3,400 is an amino protected PEG polymer with a terminal hydroxyl. The hydroxyl can further derivatize to other compound. The t-boc group can be cleaved under acidic condition using TFA or HCl. Reagent grade, for research purpose.

t-Boc-N-amido-PEG-OH, MW 5,000 is a heterofunctional PEG molecule containing amino protected group. The deprotection of t-boc can be done under acidic condition using TFA or HCl to generate a free amine (-NH2). Reagent grade, for research purpose.

t-Boc-N-amido-PEG-CH2COOH, MW 1,000 is is a linear heterofunctional polyPEG with protected amine. The carboxyl moiety can react with an amine in the presence of an activator, such as HATU or EDC. The boc protected amine can be regenerated under acidic condition to produce a free amine. Reagent grade, for research purpose.