Results for Lipids & Polymers ( 10111 )
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t-Boc-N-amido-PEG-CH2COOH, MW 5,000 is a heterofunctional PEG molecule containing carboxyl and amino protected group. In the presence of activator (EDC or HATU), a carboxyl can react with an amine to form an amide bond. The tert-boc can be deprotected under acidic condition. Reagent grade, for research purpose.
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t-Boc-N-amido-PEG-CH2COOH, MW 10,000 is is an amine protected polydisperse PEG. The carboxylic acid is reactive with amine in the presence of activating agent, such as EDC or HATU. The tert-butoxycarbonyl protecting group (t-boc) can be easily removed under acidic condition to yield a free amine which can then react with an active ester (NHS). Reagent grade, for research purpose.
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SPDP-PEG-CH2CO2H, MW 1,000 is a pyridyl disulfide modified polyPEG which can react with thiol moiety to produce a new disulfide bond and generating unreactive pyridine-2-thione as a by product. Reaction between carboxyl and amine can be done in the presence of activating agent, such as HATU/EDC, to generate amide linkage. Reagent grade, for research purpose.
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Biotin-PEG-OH, MW 5,000 is a PEG polymer with a terminal hydroxyl for biotinylation. Biotin can strongly bind to avidin or streptavidin. The Avidin-biotin complex is the strongest known non-covalent interaction (Kd = 10-15M) between a protein and ligand. The hydroxyl group can further derivatize the compound. Reagent grade, for research purpose.