Lipids & Polymers

Bis-propargyl-PEG, MW 2,000 is a homobifunctional PEG polymer with terminal alkyne. The polymer is a click chemistry reagent which can react with azide molecules in the presence of copper catalyst to form stable triazole bonds. Reagent grade, for research purpose.

nonyl 8-bromooctanoate is a chemical reagent featuring a bromide linked to a larger ester chain consisting of a C8 ester coupled to a C9 chain. Bromide is easily displaced by nucleophiles in substitution reactions. Compounds such as this may be used as intermediates in building lipids for use in lipid nanoparticles.

m-PEG-amine, MW 40,000 is a monofunctional polyPEG with a terminal amine. The coupling between NHS ester and amine produces a stable amide bond. The amine moieties is also reactive with carboxyl in the presence of activating agent, such as HATU or EDC. Reagent grade, for research purpose.

m-PEG-CH2CO2H, MW 40,000 is a carboxyl PEG polymer which can react with primary amine in the presence of activator (e.g. EDC, or HATU) to form a covalent amide linkage. Reagent grade, for research purpose.

m-PEG-CH2CO2H, MW 30,000 is a monofunctional polydisperse PEG which can react with amino molecule in the presence of activator (HATU or EDC) via amide bond formation. Reagent grade, for research purpose.

Diazo-PEG3-TCO consists of a diazo group for efficient release of captured molecules and three PEG units for enhanced water-solubility. TCO is a click chemistry handle which readily reacts with tetrazine groups on a target molecule.

DSPE-Alkyne is a phospholipid compound with two 18-carbon lipid tails and a phosphate head joined by a glycerol molecule. The molecule can self-assemble in water to form lipid bilayer with hydrophobic tails facing the inner area an d hydrophilic head facing outward interacting with water. The compound can be used to prepare nanoparticles or liposomes for drug nanocarrier to deliver therapeutics, such as mRNA/DNA vaccine. The alkyne group enables click reaction with azido molecule in the presence of Cu catalyst. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-Biotin has strong binding with avidin or streptavidin for protein labelling or purification. The compound has phospholipid group with a hydrophilic phosphate connected to two fatty acids by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-glutaric acid is a phospholipid compound with two 18-carbon lipid tails and a phosphate joined by a glycerol molecule. The molecule can self-assemble in water to form lipid bilayer with hydrophobic tails facing the inner area an d hydrophilic head facing outward interacting with water. The compound can be used to prepare nanoparticles or liposomes for drug nanocarrier to deliver therapeutics, such as mRNA/DNA vaccine. The carboxylic acid moiety can be used for bioconjugation with amine in the presence of activating agent, such as HATU or EDC. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.