Lipids & Polymers

BP Lipid 210 is an ionizable lipid used to prepare lipid nanoparitlcels (LNPs). The lipid has ethanolamine as a lipid head group which enhances the mRNA encapsulation and provides exceptional physiochemical properties. The esters of the lipid are at the C10 and C8 position relative to the amine. The primary ester has a relatively long lipid tail (9 carbons). The lipid can be used for mRNA delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 211 is an ethanolamine ionizable lipid with 9 carbon of primary-ester lipid tail. The ethanolamine head helps with mRNA encapsulation. Both ester bonds are located at C10 position relative to the amine nitrogen. The introduction of ester linkages can improve the clearance of the lipid in the liver. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 212 is an amino ionizable lipid analogous to BP-25499. The ethanolamine amino lipid head enhances encapsulation of mRNA. The lipid has primary esters at C8 and C10 position relative to the amine nitrogen. The primary ester has lipid a long 11-carbons tail. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 213 is an amino lipid with ester bonds located at C10 and C8 position relative to nitrogen amine. The ethanolamine head can effectively enhance mRNA encapsulation while ester bonds improve tissue clearance. The primary lipid tail contains 11 carbons. The ionizable lipid can be used for mRNA delivery due to its excellent physiochemical properties. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 214 is an inonizable amine lipid with two ester linkages at C10 position relative to amine. The primary C10 ester has a long 11 carbons lipid tail. The head of lipid is ethanolamine which can effectively encapsulate mRNA used in gene therapies which depends on the availability of a safe and efficient delivery vehicle. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-amine TFA salt is a simple building block containing a DBCO moiety and an amine group. Amine is very reactive with NHS ester. DBCO is commonly used for copper-free Click Chemistry reactions.

Boc-Gly-Gly is a peptide linker. The Boc group can be deprotected under mild acidic conditions to form the free amine.

DL-Thioctic acid contains a lipoic acid group and a terminal carboxylic acid group. The carboxylic acid groups can undergo sequential amide coupling reaction with amine-bearing biomolecules in the presence of EDC, HATU, and DCC to form stable amide bonds.

1-Bromoundecane is a chemical reagent featuring a bromide along a saturated C11 chain. Bromide is easily displaced by nucleophiles such as alcohols or amines. Compounds such as this may be used as intermediates in building lipids for use in lipid nanoparticles.