PEG

NH-bis(PEG2-propargyl) is a multi-branched linker with two terminal propargyl groups and an amino group. The propargyl groups reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry to yield a stable triazole linkage. The amino group is reactive with carboxylic acids, activated NHS esters, and carbonyls. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG6-NH-Boc is a Biotin compound with a Boc protected amine moiety. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Ms-PEG8-Ms is a PEG linker with two mesyl groups. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

NH-bis(PEG1-azide) is a PEG linker containing an amino group with two azide groups. The amino group is reactive with carboxylic acids, activated NHS esters. The azide groups enable PEGylation via Click Chemistry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Hydroxy-PEG4-CH2CO2H sodium salt is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Hydroxy-PEG3)-N-Boc-PEG4-t-butyl ester is a small PEG compound with a hydroxy group, a t-butyl ester, and an n-Boc moiety. The hydroxy groups can be derivatized or replaceedwith other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions. N-Boc can be removed under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent. it can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Hydroxy-PEG5-methyl ester is a PEG linker containing a hydroxyl group and a methyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Methyl ester can be hydrolyzed under strong basic condition. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Aminooxy-PEG3-t-butyl ester is an aminooxy-containing PEG compound. The aminooxy group is reactive with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The t-butyl ester can be converted tofree acid under acidic condition. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.