PEG

t-butyoxycarboxy-PEG4-phosphonic acid ethyl ester contains a t-Boc protecting group and a phosphonic acid ethyl ester moiety. The t-butyl group is removed under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azidoethyl-SS-propionic acid is a Click Chemistry-ready crosslinker. The azide group enables Click Chemistry. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The disulfide bond can be cleaved by Dithiothreitol (DTT) reagent Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azidoethyl-SS-propionic NHS ester is a Click Chemistry crosslinker. The azide group enables Click Chemistry reactions with alkynes, DBCO and BCN. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The disulfide bond can be cleaved by Dithiothreitol (DTT) reagent Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DOTA-PEG5-amine contains a DOTA moiety which can be used as a chelating agent for cations and is commonly used for imaging diagnostics. The amine group is reactive toward carboxylic acids, activated NHS esters, etc. The hydrophilic PEG chain enhances the solubility of compounds in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG36-acid is a long chain, monodisperse PEG reagent with a TCO function group. The terminal carboxylic acid can react with primary amine groups in the presence o EDC to form an amide bond. This reagent can react with tetrazine-containing compounds without the catalysis of Cu or elevated temperatures. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DOTA-PEG5-C6-DBCO is a PEG linker containing DOTA and DBCO moieties. DBCO is used in Click Chemistry reactions due to its high strain energy. The DOTA group can be ionized and is susceptible for chelating di- and trivalent cations. DOTA can also be used for imaging diagnostic techniques. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Ms-PEG10-t-butyl ester is a PEG linker containing a mesyl group and a t-butyl ester moiety. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions and allowing for the carboxylic acid to react with primary amines in the presence of activators such as EDC and HATU. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG12-acid is a aqueous soluble PEG linker attached with TCO moiety. The terminal carboxylic acid can react with primary amine groups in the presence of EDC. This reagent can react with tetrazine-containing molecule to form a stable covalent bond . The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG3-triethoxysilane is a PEG linker containing azido and triethoxysilane moieties. The azide can be used for copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN. The triethoxysilane moiety is used for surface modification. The hydrophilic PEG linkers increase the water solubility properties of compounds in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.