PEG

NH-bis(PEG4-acid) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

NHPI-PEG4-C2-NHS ester (WO2014185985A1) is a chemical compound employed as a linker in the formation of antibody-drug conjugates (ADC)[1].

NHPI-PEG4-C2-Pfp ester is utilized as a linker for antibody-drug conjugates (ADC).

PC Alkyne-PEG4-NHS ester is a cleavable 4-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

PEG4-SPDP, a cleavable ADC linker, is utilized in antibody-drug conjugates (ADCs).

Pomalidomide-amido-PEG3-C2-NH2, known as Cereblon Ligand-Linker Conjugates 22, is a synthesized E3 ligase ligand-linker conjugate designed for use in PROTAC technology. It consists of the Pomalidomide-based cereblon ligand and a 3-unit PEG linker. [1]

Pomalidomide-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Pomalidomide-PEG6-butyl iodide is a chemically synthesized E3 ligase ligand-linker conjugate, combining the cereblon ligand from Pomalidomide with a 6-unit PEG linker, commonly used in PROTAC technology [1].

Propargyl-O-C1-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.