PEG

Bis-PEG18-NHS ester is a homobifunctional PEG linker featuring two NHS esters, which easily react with nucleophiles such as primary amines and alcohols to form amides or esters respectively.

BB1-NHS ester is amine reactive at pH 7-9 to form a stable, irreversible amide bond. It was used in a unique chemselective "unclickable' bioconjugation strategy to site specifically modify proteins. Ref: P. Andy, S. ERickson, J. Italia, A. Chatterjee, JACS, 2017, 139 (34), 11670-11673 Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BB1-acid was used in a unique chemselective "unclickable' bioconjugation strategy to site specifically modify proteins. Ref: P. Andy, S. ERickson, J. Italia, A. Chatterjee, JACS, 2017, 139 (34), 11670-11673 Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azide-PEG2-Tos is a small PEG linker featuring an azide and a tosylate. Tosylates are good leaving groups which are easily displaced by nucleophiles while azide is a click chemistry handle which is used to react with terminal alkynes or strained cyclooctynes.

TCO-PEG6-TCO is a homobifunctional PEG linker featuring a two trans-cyclooctenes. TCO is a click chemistry handle which readily reacts with tetrazine-containing compounds.

Bis-PEG13-TFP ester is a homobifunctional PEG linker featuring two TFP esters, which easily react with nucleophiles such as primary amines and alcohols to form amides or esters respectively. TFP esters are more stable and less reactive than their NHS counterparts.

Bis-propargyl-PEG, MW 2,000 is a homobifunctional PEG polymer with terminal alkyne. The polymer is a click chemistry reagent which can react with azide molecules in the presence of copper catalyst to form stable triazole bonds. Reagent grade, for research purpose.

m-PEG-amine, MW 40,000 is a monofunctional polyPEG with a terminal amine. The coupling between NHS ester and amine produces a stable amide bond. The amine moieties is also reactive with carboxyl in the presence of activating agent, such as HATU or EDC. Reagent grade, for research purpose.

m-PEG-CH2CO2H, MW 40,000 is a carboxyl PEG polymer which can react with primary amine in the presence of activator (e.g. EDC, or HATU) to form a covalent amide linkage. Reagent grade, for research purpose.