PEG

DMG (1,2-Dimyristoyl-rac-glycerol) is a carboxylic ester, glycerolipid and diglyceride with an attached myristoyl group, promoting interactions between proteins and lipids. It can be employed as a detergent or reagent. It’s functional in cell biology experimentation concerning metabolism and metabolic pathways involving glycerolipids. As a diglyceride, the substance consists of two fatty acid chains covalently bonded to the glycerol molecule in the 1,2- formation. Diglyceride (DAG) research investigates the process of suppressing fat accumulation through DAG consumption. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

NHS-PEG1-SS-PEG1-NHS is a homobifunctional PEG linker featuring two NHS groups linked at a disulfide bond. NHS is easily displaced by nucleophiles such as amines while the disulfide bond is cleavable under reducing conditions such as those found in the cell cytoplasm.

N-(Amino-PEG4)-N-Fluorescein-PEG4-acid is a branched PEG linker containing a fluorescent dye, a primary amine, and a carboxylic acid group. Fluorescein is a near-UV/Vis spectrum dye. The primary amine is available for use as a nucleophile, while the carboxylic acid can be used as a scaffold for amide couplings or for forming heterocyclic compounds. The PEG linker provides aqueous solubility.

m-PEG11-Ms is a PEG linker featuring a methoxy cap and a mesylate group. The methoxy cap is inert while the mesylate is a good leaving group which is easily displaced by nucleophiles such as alcohols and amines.

DBCO-PEG8-NH-Boc is a PEG linker with a DBCO group and a Boc-protected amine. The DBCO can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions to further react. The hydrophilic PEG linker increases the water solubility of the compound.

(S)-4-(4,7-Bis(2-(tert-butoxy)-2-oxoethyl)-1,4,7-triazonan-1-yl)-5-(tert-butoxy)-5-oxopentanoic acid is a bifunctional chelating agent with three t-butyl groups and one acid group that shows high complexation constant with metals. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2-(4,7-Bis(2-(tert-butoxy)-2-oxoethyl)-1,4,7-triazonan-1-yl)acetic acid is a bifunctional chelating agent with two t-butyl groups and one acid group that shows high complexation constant with metals. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

NOTA is a bifunctional chelating agent that shows high complexation constant with metals, such as gallium. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-S-S-PEG-silane, MW 2,000 is a cleavable reagent for introduction of a biotin moiety to silane with hydroxyl (OH) functional group. PEG spacer arm provides better solubility to the labeled molecules in aqueous media. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME, and TCEP.