PEG

PLA(2k)-PEG(2k)-COOH is a micelle-forming polymer for hydrophobic drug encapsulation in drug delivery system. The polymer has terminal carboxyl which can react with amine molecule to form a stable amide linkage in presence of activator, such as HATU or EDC. The PLA is made of racemic (D,L-lactide). Reagent grade, for research purpose.

PLA(2k)-PEG(5k)-COOH has a racemic PLA hydrophobic block and a PEG hydrophilic block tethered with carboxyl which is reactive with amine in the presence of activating agent, such as HATU or EDC, to form a stable amide linkage. The polymer can self-assemble to form micelles in water and be used to encapsulate drugs in drug delivery. Reagent grade, for research purpose.

PLA(2k)-PEG(2k)-MAL is a self-assembling block copolymer with racemic PLA as hydrophobic segment and PEG as hydrophilic block. The maleimide is reactive with thiol molecule to form a stable thioether linkage. The polymer can be used to prepare drug loaded nanoparticles for targeted delivery. Reagent grade, for research purpose.

PLA(2k)-PEG(3k)-MAL is a block copolymer containing racemic PLA (hydrophobic) and PEG (hydrophilic). Upon dispersion in water, the polymer self-assembles to form micelles with PLA core and PEG shell. The core can be used as reservoir for hydrophobic drugs while the shell can provide protection from degradation (enzymatic/hydrolysis). The maleimide is reactive with thiol molecule at pH 6.5-7.5 Reagent grade, for research purpose.

PLA(5k)-PEG(1k)-MAL is an amphiphile polymer with hydrophobic racemic poly(lactide) and hydrophilic PEG. The self-assembling polymer forms micelles which can be used to entrap hydrophobic drugs. The terminal maleimide can react with thiol via formation of thioether linkage. Reagent grade, for research purpose.

PLA(5k)-PEG(5k)-MAL allows self assembly when dispersed in water. The micelle structure contains hydrophobic core (racemic PLA) and hydrophilic shell (PEG). It can be used to prepare drug nanocarrier in drug delivery system. The maleimide is reactive with thiol to form a stable thioether linkage. Reagent grade, for research purpose.

PLA(5k)-PEG(2k)-N3 is a monofunctional block copolymer with hydrophobic PLA (racemic) block and hydrophilic PEG segment. The amphiphilic polymer has terminal azide which can undergo click reaction with alkyne molecule, such as DBCO/BCN or terminal alkyne (with Cu catalyst), via triazole bond formation. It can be used to prepare nanoparticles for drug delivery. Reagent grade, for research purpose.

PLA(5k)-PEG(5k)-NH2 has terminal amine which can react readily with an active NHS ester or with a carboxylic acid in the presence of HATU/EDC. The polymer contains both hydrophobic (PLA) and hydrophilic (PEG) blocks. It can self-assemble in water to form nanoparticles/micelles which can be used to encapsulate biopharmaceutical drugs. Reagent grade, for research purpose.

ACRL-PLA(1k)-PEG(3k)-PLA(1k)-ACRL is a self-assembling triblock copolymer. Acrylate groups are attached on each terminal of the polymer which can be used for radical initiated polymerization to form hydrogel. The polymer is biodegradable via hydrolysis of the ester bonds. Reagent grade, for research purpose.