PEG

ACRL-PLA(2k)-PEG(1k)-PLA(2k)-ACRL contains hydrophilic PEG block in between hydrophobic PLA (racemic) blocks. Upon dispersion in water, the polymer can self-assemble to form micelles and can be used to encapsulate hydrophobic drugs. The ester bonds of PLA is biodegradable via hydrolysis which can be useful for controlled release drug delivery. The terminal acrylates can be polymerized in the presence of radical initiator. Reagent grade, for research purpose.

ACRL-PLA(2k)-PEG(3k)-PLA(2k)-ACRL is a micelle-forming ABA triblock amphiphilic polymer. The polymer can be used for nanocarrier formulation for controlled drug delivery. The acrylate moieties can be polymerized in the presence of radical/UV initiator. Reagent grade, for research purpose.

PLLA(5k)-PEG(2k)-NHS is an amphipathic block copolymer with NHS ester which can react with amine nucleophile via amide bond formation. The self-assembling polymer can be used to prepare nanoparticles for drug delivery. Reagent grade, for research purpose.

N-(alcohol-PEG2)-N-bis(PEG2-propargyl) has a hydroxyl group and two propargyl groups. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The propargyl groups can participate in copper catalyzed azide-alkyne Click Chemistry.

NH2-PLGA(10k)-PEG(5k)-MAL is a heterobifunctional amphiphilic block copolymer. The N-terminus is reactive with an NHS ester readily or with a carboxylic acid (COOH) in the presence of HATU or EDC. The terminal maleimide can react with thiol molecule via thioether bond formation. The polymer can self assemble in water to form nanomicellar which can be used for controlled release drug delivery. Reagent grade, for research purpose.

PLGA(2k)-mPEG(5k) can be used to prepare nanoparticles for drug delivery applications. The polymer contains a hydrophobic poly(lactide-co-glycolide) (PLGA) block attached to a hydrophilic PEG block. The polyester PLGA allows hydrolytic degradation on the ester bonds. Reagent grade, for research purpose.

PLGA(5k)-mPEG(2k) is a diblock amphiphile polymer which forms micelles upon dispersion in water. The polymeric micelles consists of hydrophobic core-forming block poly(lactide-co-glycolide) (PLGA) and hydrophilic shell-forming PEG block. It can be used to encapsulate drugs for nanomedicine/drug delivery. The polyester PLGA is biodegradable via hydrolysis on the ester bonds. Reagent grade, for research purpose.

PLGA(5k)-mPEG(5k) is made of two distinct polymers with different hydrophilicity. One of the block is hydrophilic PEG and the other one is hydrophobic poly(lactide-co-glycolide) (PLGA). The different hydrophilicity allows the polymer to self-assemble in water with arrangement of PEG facing the water surface and PLGA being shieled from the water. The core regions can be used to encapsulate hydrophobic drugs for sustained drug delivery. Reagent grade, for research purpose.

PLGA(10k)-mPEG(2k) is an amphipathic polymer which can self-assemble in water. The hydrophobic poly(lactide-co-glycolide) (PLGA) segment can be used to entrap hydrophobic therapeutics while the PEG block can form a tight shell around the core due to hydrogen bonds interaction with water. The terminal hydroxyl group of the PLGA can be further derivatized. Reagent grade, for research purpose.