PEG

PLGA(10k)-mPEG(5k) is an amphiphilic block copolymer with hydrophobic poly(lactide-co-glycolide) (PLGA) and hydrophilic PEG. The polymer can be used as a drug carrier in nanomedicine and targeted delivery. The hydroxyl terminus allows further derivatization. Reagent grade, for research purpose.

PLGA(20k)-mPEG(2k) is an amphiphilic block copolymer which can self-assemble in aqueous media to form micelles. The copolymer contains poly(lactide-co-glycolide) (PLGA) as a hydrophobic segment and PEG as a hydrophilic block. The polymer is biodegradable and can be used as vesicles by encapsulating hydrophobic drugs in its hydrophobic regions. Reagent grade, for research purpose.

PLGA(20k)-mPEG(5k) is a block copolymer containing a hydrophobic poly(lactide-co-glycolide) (PLGA) block and a hydrophilic PEG segment. Upon water dispersion, the polymer self-assembles to form micelles with the PLGA being shielded from the water (core) and the PEG facing the water (shell). The core of micelles can serve as reservoirs for hydrophobic drugs while the shell regions provide tight shell around the core which can minimize degradation. Reagent grade, for research purpose.

PLGA(30k)-mPEG(5k) is a self-assembling block copolymer with poly(lactide-co-glycolide) (PLGA) as hydrophobic segment and PEG as hydrophilic block. The polymer can be used to prepare drug loaded nanoparticles where the core PLGA regions serve as reservoirs for hydrophobic drugs. Reagent grade, for research purpose.

PLGA(40k)-mPEG(5k) is a block copolymer with a hydrophobic poly(lactide-co-glycolide) (PLGA) segment chemically tethered to a hydrophilic PEG block. The polymer is micelle-forming and biodegradable. It can be used to encapsulate hydrophobic drugs in the core region of the micelles. Reagent grade, for research purpose.

mPEG(2k)-PLGA(2k)-Thiol enables self-assembly to form micelles with the arrangment of poly(lactide-co-glycolide) (PLGA) core and PEG shell. The core regions can serve as hydrophobic drugs reservoir while the shell can provide protection against degradation. Moreover, the PEG shell also allows the "stealth behavior" which is a prerequisite for successful in vivo translation of nanomedicine to achieve long blood circulation and targeted delivery. The ester bonds of the polymer can be degraded via hydrolysis. The thiol moiety, attched to PLGA, is reactive with maleimide or SPDP. Reagent grade, for research purpose.

mPEG(2k)-PLGA(10k)-Thiol comprises two distinct hydrophobicity blocks, i.e. poly(lactide-co-glycolide) (PLGA) as a hydrophobic block and PEG as a hydrophilic block. It has terminal thiol, attached to PLGA, for reaction with maleimide via thioether bond formation. The polymer can self-assemble in aqueous media and be used as strategies for sustained drug delivery using micellar nanocarriers. Reagent grade, for research purpose.

PLGA(10k)-PEG(5k)-ALK is a polymer with both hydrophobic (poly(lactide-co-glycolide)/PLGA) and hydrophilic (PEG) blocks. The self-assembly of the polymer in water occurs with PLGA being shielded at the core by PEG shell. The hydrophobic core can be used to encapsulate lipophilic drugs while the PEG shell offers protection against (enzymatic/hydrolysis) degradation in drug delivery/nanomedicine. Reagent grade, for research purpose.

PLGA(10k)-PEG(2k)-COOH is one of bioconjugation amphiphilic polymers which can react with amine molecule, such as protein or peptide, in the presence of activating agent (HATU or EDC). The polymer forms micelles in water where the core contains poly(lactide-co-glycolide) (PLGA) and the shell is made of PEG. This polymer can be used to prepare nanocarrier for therapeutic agents/drugs. Reagent grade, for research purpose.