PEG

4-Oxobutanoic acid methyl ester

m-PEG-OH, MW 30,000 is a polyPEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

N-(Azido-PEG1)-N-bis(PEG3-t-butyl ester) is a branched PEG reagent containing an azide group with two t-butyl esters. The t-butyl group can be deprotected under acidic conditions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

N-(Azido-PEG1)-N-bis(PEG2-t-butyl ester) is a branched PEG reagent containing an azide group with two t-butyl esters. The t-butyl group can be deprotected under acidic conditions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Biotin-PEG24-NHS ester is an amine reactive biotinylation reagent that can couple with amine-containing molecules. The NHS group reacts specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form stable amide bonds.

N-(Azido-PEG1)-N-bis(PEG3-acid), HCl salt is a PEG compound that contains terminal biotin and carboxylic acid moieties. Biotin can be used for the conjugation of proteins and biotin labeling. The carboxylic acid groups can undergo sequential amide coupling reactions with amine-bearing biomolecules in the presence of EDC, HATU and DCC to form stable amide bonds.

N-(Azido-PEG1)-N-bis(PEG2-acid), HCl salt is a PEG compound that contains terminal biotin and carboxylic acid moieties. Biotin can be used for the conjugation of proteins and biotin labeling. The carboxylic acid groups can undergo sequential amide coupling reactions with amine-bearing biomolecules in the presence of EDC, HATU and DCC to form stable amide bonds.

4-(5-Nitropyridin-2-yl)disulfanyl)pentanoic acid is a synthetic building block with terminal nitro and carboxylic acid groups with a disulfide bond in the center.

t-Butoxycarbonyl-PEG3-NHS ester has a t-Boc protecting group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic conditions to form a covalent bond. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.