PEG

t-Boc-N-amido-PEG12-NHS ester is a PEG linker containing a Boc-protected amino group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The protected amine can be deprotected in acidic conditions.

t-Boc-N-amido-PEG16-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form the free amine.

t-Boc-N-amido-PEG16-NHS ester is a PEG linker containing an NHS ester and a Boc-protected amino group. The Boc group can be deprotected under mild acidic conditions to form the free amine. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

(S, R, S)-AHPC-nanoly-acid is a PROTAC linker that incorporates an E3 ligase ligand with a linker to empower PROTAC drug research & discovery. It can react with amine containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Thalidomide-O-Hexyl-Acid is an E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and an alkane linker used in PROTAC technology.

6-Azidohexanoic Acid STP Ester is an amine-reactive, water-soluble labeling reagent with an azide group and a terminal 4-Sulfo-2,3,5,6-tetrafluorophenyl (STP) group. 6-Azidohexanoic Acid STP Ester is used to modify proteins, antibodies, and other amine-containing biopolymers in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. STP esters can react with primary amines, forming covalent amide bonds, and typically display much better stability toward hydrolysis in aqueous media, resulting in more efficiency and better reproducible labeling of biopolymers.

6-Azidohexanoic Acid Sulfo-NHS Ester is an amine-reactive, water-soluble labeling reagent with an azide group and a terminal sulfo-NHS ester group. It is used to modify proteins, antibodies, and other amine-containing biopolymers in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Sulfo-NHS Esters react with primary amines to form stable amide bonds and is useful for applications that cannot tolerate organic co-solvents or are complicated by their inclusion.

Iodoacetamide Azide is a molecule consisting of an azide and a terminal iodide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The iodoacetamide group is an alkylating agent that can be used to bind covalently with the thiol group. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin Azide Plus is a biotinylation reagent used for labeing glycoproteins, carbohydrate-containing compounds that have oxidizable sugars or aldehydes. Biotin Azide Plus is a complete copper-chelating system that acts simultaneously as both reactant and catalyst in CuAAC reactions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The reaction works well under diluted conditions.