PEG

Thalidomide-5,6-F is used in the recruitment of the cereblon protein and is also used as a PROTAC linker.

2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione is a derivative of thalidomide with an iodine atom on the benzyl ring

2-Chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide is a derivative of thalidomide with an chloroacetamide group on the benzyl ring.

3-(4-Bromo-7-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a derivative of thalidomide with a flouride and bromide groups on the benzyl ring.

2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride is a hydrochloride salt derivative of thalidomide with a flouride atom and piperazine group on the benzyl ring.

5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a derivative of thalidomide with a bromide atom on the benzyl ring.

4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a derivative of thalidomide with an amine group on the benzyl ring.

E3 Ligase ligand 9 targets ubiquitin-protein ligases in order to activate the E3 ubiquitin ligase.

Thalidomide-O-C6-Amine HCl is a functionalized cereblon ligand used for PROTAC research. It incorporates an E3 ligase ligand and a C6 alkyl linker to conjugate to a target protein.