PEG

DBCO-PEG-NH-Boc, MW 5,000 is a polyPEG linker with a DBCO group and a Boc-protected amine. The DBCO can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions to further react. The PEG chain helps with water solublity and flexibilty of the crosslinking agent. Reagent grade, for research purpose.

Carboxy-Amido-PEG5-Amine is a PEG reagent containing an amino (NH2) and a terminal carboxylic acid group. NH2 amine group is reactive with carboxylic acids in the presence of coupling reagents such as EDC, or directly with NHS esters, to form a stable amide bond. The hydrophilic PEG unit increases hydrophilicity. Reagent grade, for research purpose.

Carboxy-Amido-PEG5-N-Boc is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. Reagent grade, for research purpose.

N-(t-butyl ester-PEG6)-N-bis(PEG6-azide) is a 3-arm PEG reagent with a t-butyl ester group and two azide groups. The t-butyl ester group can be deprotected under acidic conditions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Reagent grade, for research purpose.

DBCO-PEG-amine, MW 5,000 is a polyPEG linker which contains DBCO and amine moieties. The DBCO group is commonly used in copper-free Click Chemistry reactions. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG spacer increases the water solubility of the compound. Reagent grade, for research use only.

Palmityl-C6 amino phosphoramidite is a saturated fatty acid with a 16-carbon tail and a terminal propargyl group on the phosphoramidite head. Reagent grade, for research purpose.

(2,2-dimethyl-1,3-dioxan-5-yl)methyl 6-bromohexanoate is a small molecule with an acetonide protection group and a terminal bromine. The bromine (Br) is a very good leaving group for nucleophilic substitution reactions. Acetonide protection can be removed by hydrolysis of the ketal using a dilute aqueous acid. Reagent grade, for research purpose.

3-Arm PEG5-Azide is a PEG linker containing three terminal azide groups. The azide groups enables PEGylation via Click Chemistry. Reagent grade, for research purpose.

3-Arm PEG5-Amine is a PEG linker containing three terminal amine groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. Reagent grade, for research purpose.