PEG

16-(tert-Butoxy)-16-oxohexadecanoic acid is a linker containing a hydroxyl group with a carboxylic acid. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond. Reagent grade, for research purpose.

2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid is a linker containing a maleimide group with a terminal carboxylic acid. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid can be used in the synthesis of glycan probes. Reagent grade, for research purpose.

Benzyl-PEG-OH, 5,000 MW is a polyPEG linker with a benzyl protecting group and a reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic polyPEG linker increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose.

DBCO-PEG6-amine is a PEG linker which contains DBCO and amine moieties. The DBCO group is commonly used in copper-free Click Chemistry reactions. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG spacer increases the water solubility of the compound. Reagent grade, for research purpose.

18-(NHS ester-methylamine-PEG3-ethylcarbamoyl)heptadecanoic-t-butyl ester is a PEG linker with an NHS ester group and an alkane tail that has a terminal t-butyl ester group. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The t-butyl group can be deprotected under acidic conditions. The polymer can form micelles spontaneously in water. It may also be used to prepare more complex lipids for nanoparticles for drug delivery. Reagent grade, for research purpose.

rac 1-Palmitoyl-3-chloropropanediol is a monoacylglycerol of palmitic acid at the sn-1 position and a chloride group at the sn-3 position. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The chlorine is a good leaving group and can undergo substitution reactions. Reagent grade, for research purpose.

1-Palmitoyl-2-arachidoyllecithin is a phospholipid with both saturated and unsaturated fatty acids attached by glycerol to the phosphate head. The sn-1 position contains saturated palmitic acid while the sn-2 position is made of highly unsaturated fatty acid (arachidonic acid). Reagent grade, for research purpose.

N-(Propargyl-PEG2)-PEG3-N-Boc is a branched PEG linker with an alkyne group and a t-butyl ester. The alkyne group reacts with azide-bearing compound in coppper catalyzed azide-alkyne Click Chemistry reaction. The Boc group can be deprotected under acidic conditions. The amino group is reactive with carboxylic acids, activated NHS esters, and carbonyls. Reagent grade, for research purpose.

Iodoacetamido-PEG3-t-butyl ester is a PEG reagent containing an Iodoacetamide group and a t-butyl ester. The iodoacetamide group is an alkylating agent that can be used to bind covalently with the thiol group. The t-butyl ester groups can be deprotected under acidic conditions. Reagent grade, for research purpose.