PEG

Azido-PEG-CH2CO2-NHS, MW 2,000 is a polyPEG linker containing an azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. Azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose.

DBCO-Amido-tri-(carboxyethoxymethyl)-methane is an aqueous soluble PEG linker with an DBCO group with three terminal carboxylic acids. The DBCO groups is commonly used for Click Chemistry reactions. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond. Reagent grade, for research purpose.

5'-DMTr-dA(Bz)-Methyl phosphonamidite is a nucleoside phosphonamidite with an adenine capped by a benzoyl functional group.

5'-O-DMTr-2'-O-TBDMS-N 1 -methylpseudouridine 3'-(cyanoethyl-N,N-diisopropyl)phosphoramidite is a TBDMS-protected phosphoramidite monomer eligible for special oligonucleotide synthesis.

14-(Amine-PEG6-ethylcarbamoyl)tridecanoic-t-butyl ester is a PEG linker with an amine group and an alkane tail that has a terminal t-butyl ester group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The t-butyl group can be deprotected under acidic conditions. The polymer can form micelles spontaneously in water. It may also be used to prepare more complex lipids for nanoparticles in drug delivery. Reagent grade, for research purpose.

Azido-PEG23-azide is a aqueous-soluble, homebifunctional PEG reagent. The azide (N3) group very reactive with alkynes such as BCN and DBCO via Click Chemistry to yield a stable triazole moiety. Reagent grade, for research purpose.

D-Desthiobiotin is a non-sulfur containing biotin derivative that binds less strongly to biotin-binding proteins and is easily dislocated by biotin. Reagent grade, for research purpose.

(S,R,S)-AHPC-PEG3-N3 is a VHL ligand with a PEG 3 azide linker and terminal acid for PROTAC compounds. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose.

DMG-Nitrophenyl Carbonate is a short reagent featuring a DMG lipid headgroup and a nitrophenyl carbonate, which is readily displaced by amine nucleophiles to form carbamate bonds under mild conditions.