PEG

Boc-NH-PEG10-CH2CH2NH2 is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands necessary for PROTAC molecule formation, and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

DBCO-PEG3-oxyamine is a non-cleavable, 3-unit polyethylene glycol linker used for synthesizing antibody-drug conjugates (ADCs) [1].

TCO-PEG6-acid is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Tetrazine-PEG4-SS-NHS is a cleavable four-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

C3-K2-E14 is a multi-ionizable amino-lipid featuring a central tertiary amine with two identical brranches and an n-propyl group. Each branch features a propanamide linking to a branched amine, each with two C14 arms and a hydroxyl. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug delivery.

Acid-PEG4-C2-Boc, a linker compound based on polyethylene glycol (PEG) and alkyl/ether, is utilized in the synthesis of PROteolysis TArgeting Chimeras (PROTACs) for inhibiting the mechanistic Target of Rapamycin (mTOR)[1].

Dde Biotin-PEG4-DBCO is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG4-Hydrazide is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

BCN-PEG3-VC-PFP ester, a three-unit PEG ADC linker, is cleavable and commonly used in the synthesis of antibody-drug conjugates (ADCs) [1].