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Cereblon inhibitor 1 is an isoindoline derivative which acts as a modulator of the cereblon E3 ubiquitin ligase. Its structural features make it valuable for studying cereblon-related protein interactions.

PD 4'-oxyacetic acid is a cereblon ligand featuring a carboxylic acid functional group, useful for developing PROTAC degraders.

VH101, thiol is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal thiol group, designed for PROTAC development. It enables conjugation with a target protein-ligand for use in E3 ligase-mediated degradation systems.

E3 ligase Ligand 18 is designed to target E3 ubiquitin ligase and can be linked to a protein ligand via a connector to create PROTACs, which facilitate ubiquitin-mediated degradation of specific proteins.

VH 101, acid is a functionalized von-Hippel-Lindau (VHL) ligand designed for PROTAC research. It features an E3 ligase ligand and an alkyl linker with a terminal amine, facilitating conjugation to a target protein ligand.

AR antagonist 1 is a potent androgen receptor (AR) antagonist that interacts with E3 ligase ligands, showing weak binding affinity to the VHL protein in the synthesis of PROTAC ARD-266.

E3 ligase Ligand 23 is a cereblon binder that facilitates the degradation of the Ikaros or Aiolos transcription factors through the ubiquitin-proteasome pathway.

(4R,5S)-Nutlin carboxylic acid is a Nutlin 3-derived ligand that targets MDM2. It can be linked to a protein ligand via a connector to create PROTACs.

CC-3060 is a cereblon modulator that facilitates the degradation of ZBTB16. It selectively targets ZBTB16 by engaging specific structural degrons across its zinc finger domains.