Other Proteins

Recombinant Murine SF-20 (Legacy Tebubio ref. 167210-25). Murine SF-20 is a bone marrow stroma-derived growth factor. SF-20 is expressed in bone marrow, spleen stroma cells, resting mononuclear cells, resting CD8+ and CD19+ cells, and activated CD8+ T cells, and has been shown to bind to the surface of cells expressing the receptor TSA-1 (Thymic shared Ag-1). Among its biological activities, SF-20 stimulates the proliferation of FDC-P2 cells (a mouse factor-dependent hemopoietic cell line) and mouse lymphoid cells. Recombinant Murine SF-20 is a 15.8 kDa protein containing 143 amino acid residues.

Recombinant Murine SF-20 (Legacy Tebubio ref. 167210-25). Murine SF-20 is a bone marrow stroma-derived growth factor. SF-20 is expressed in bone marrow, spleen stroma cells, resting mononuclear cells, resting CD8+ and CD19+ cells, and activated CD8+ T cells, and has been shown to bind to the surface of cells expressing the receptor TSA-1 (Thymic shared Ag-1). Among its biological activities, SF-20 stimulates the proliferation of FDC-P2 cells (a mouse factor-dependent hemopoietic cell line) and mouse lymphoid cells. Recombinant Murine SF-20 is a 15.8 kDa protein containing 143 amino acid residues.

Recombinant Murine IL-36RA (Legacy Tebubio ref. 167210-36RA). The IL-1 family is comprised of 11 structurally related ligands, including the recently re-named IL-36RA (IL-1F5), IL-36alpha (IL-1F6), IL-36beta (IL-1F8), and IL-36gamma (IL-1F9). The interaction of IL-36 ligands with the IL-1Rrp2 receptor (IL-1R6) can induce various activities, including dendritic cell maturation and activation. IL-36RA can antagonize the NF-kappaB signaling induced by either IL-36alpha, beta or gamma by binding to the IL-1Rrp2 receptor in a manner that prevents the initiation of functional signaling. Recombinant Murine IL-36RA is an E.coli-derived 16.9 kDa protein containing 154 amino acid residues.

Recombinant Murine IL-36RA (Legacy Tebubio ref. 167210-36RA). The IL-1 family is comprised of 11 structurally related ligands, including the recently re-named IL-36RA (IL-1F5), IL-36alpha (IL-1F6), IL-36beta (IL-1F8), and IL-36gamma (IL-1F9). The interaction of IL-36 ligands with the IL-1Rrp2 receptor (IL-1R6) can induce various activities, including dendritic cell maturation and activation. IL-36RA can antagonize the NF-kappaB signaling induced by either IL-36alpha, beta or gamma by binding to the IL-1Rrp2 receptor in a manner that prevents the initiation of functional signaling. Recombinant Murine IL-36RA is an E.coli-derived 16.9 kDa protein containing 154 amino acid residues.

Recombinant Murine IL-2 (Legacy Tebubio ref. 167212-12). IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Murine IL-2 is a 17.2 kDa protein containing 148 amino acid residues.

Recombinant Murine IL-2 (Legacy Tebubio ref. 167212-12). IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Murine IL-2 is a 17.2 kDa protein containing 148 amino acid residues.

Recombinant Murine IL-5 (Legacy Tebubio ref. 167215-15). IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant Murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Recombinant Murine IL-5 (Legacy Tebubio ref. 167215-15). IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant Murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Recombinant Murine IL-7 (Legacy Tebubio ref. 167217-17). IL-7 is a hematopoietic growth factor that primarily affects early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant Murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.