Other Proteins

Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine produced by thymus tissue constitutively and activated PBMCs (mainly DCs). TARC signals through the CCR4 receptor to induce chemotaxis of Th2 cells. TARC is thought to be important in asthma and allergic diseases, along with bacterial and viral infections. Recombinant human TARC is a non-glycosylated protein, containing 71 amino acids, with a molecular weight of 8.1 kDa.

Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine produced by thymus tissue constitutively and activated PBMCs (mainly DCs). TARC signals through the CCR4 receptor to induce chemotaxis of Th2 cells. TARC is thought to be important in asthma and allergic diseases, along with bacterial and viral infections. Recombinant human TARC is a non-glycosylated protein, containing 71 amino acids, with a molecular weight of 8.1 kDa.

Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine produced by thymus tissue constitutively and activated PBMCs (mainly DCs). TARC signals through the CCR4 receptor to induce chemotaxis of Th2 cells. TARC is thought to be important in asthma and allergic diseases, along with bacterial and viral infections. Recombinant human TARC is a non-glycosylated protein, containing 71 amino acids, with a molecular weight of 8.1 kDa.

Transforming Growth Factor-beta 1 (TGF-β1) is a member of the TGF-beta superfamily. Members of this family are known to exhibit regulatory activity in immunity and proliferation pathways. TGF-β1 signals through SMAD proteins via the TGF-β1 RI and RII receptors. Mature human TGF-β1 is a glycosylated homodimer, containing two 112 amino acids chains, with a total molecular weight of 25 kDa.

Transforming Growth Factor-beta 1 (TGF-β1) is a member of the TGF-beta superfamily. Members of this family are known to exhibit regulatory activity in immunity and proliferation pathways. TGF-β1 signals through SMAD proteins via the TGF-β1 RI and RII receptors. Mature human TGF-β1 is a glycosylated homodimer, containing two 112 amino acids chains, with a total molecular weight of 25 kDa.

TNF Receptor 1 (TNFR1) is expressed in most tissues and is activated by soluble and membrane-bound TNFα. TNFR1 is known to activate NF-kB and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis and inhibit viral replication. The soluble form of recombinant human TNFR1 is a non-glycosylated protein, containing 162 amino acids, with a molecular weight of 18.3 kDa.

TNF Receptor 1 (TNFR1) is expressed in most tissues and is activated by soluble and membrane-bound TNFα. TNFR1 is known to activate NF-kB and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis and inhibit viral replication. The soluble form of recombinant human TNFR1 is a non-glycosylated protein, containing 162 amino acids, with a molecular weight of 18.3 kDa.

TNF Receptor 1 (TNFR1) is expressed in most tissues and is activated by soluble and membrane-bound TNFα. TNFR1 is known to activate NF-kB and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis and inhibit viral replication. The soluble form of recombinant human TNFR1 is a non-glycosylated protein, containing 162 amino acids, with a molecular weight of 18.3 kDa.

TNF-Related Apoptosis-Inducing Ligand (TRAIL) is produced by a wide variety of cell types and is shown to be a cytotoxic protein that induces apoptosis in tumor cells through activation of the death receptors, DR4 and DR5. Human TRAIL is active on mouse cells. Recombinant human TRAIL is a non-glycosylated protein, containing the 168 amino acid extracellular portion of TRAIL that is homologous to TNF. It has a molecular weight of 19.5 kDa.