Other Proteins

Interferon Inducible T cell Alpha Chemokine (I-TAC), or CXCL11, expressed at high levels in leukocytes, pancreas and liver exposed to IFNα, β, and γ. I-TAC is one of three chemokines known to bind the receptor CXCR3 (the two others being CXCL9 and CXCL10 (IP-10)) to act as a chemoattractant for IL-2 activated T cells. CXCL11 differs from the other CXCR3 ligands in that it has a higher receptor affinity, thus acts as a stronger agonist. Recombinant human I-TAC is a non-glycosylated protein, containing 73 amino acids, with a molecular weight of 8.3 kDa.

Human Leukemia Inhibitory Factor (LIF) is member of the IL-6 family and is made by a variety of tissues. Human LIF signals through gp130 to activate STAT3 in human ESCs . In mouse ESCs, LIF promotes self-renewal and pluripotency, but in human cells there is no indication that LIF has the same function. Instead, FGF-basic (FGF-2) and Activin A are used to promote self-renewal and pluripotent potential. Recombinant human LIF is a non-glycosylated protein, containing 181 amino acids, with a molecular weight of 19.9 kDa.

Human Leukemia Inhibitory Factor (LIF) is member of the IL-6 family and is made by a variety of tissues. Human LIF signals through gp130 to activate STAT3 in human ESCs . In mouse ESCs, LIF promotes self-renewal and pluripotency, but in human cells there is no indication that LIF has the same function. Instead, FGF-basic (FGF-2) and Activin A are used to promote self-renewal and pluripotent potential. Recombinant human LIF is a non-glycosylated protein, containing 181 amino acids, with a molecular weight of 19.9 kDa.

Human Leukemia Inhibitory Factor (LIF) is member of the IL-6 family and is made by a variety of tissues. Human LIF signals through gp130 to activate STAT3 in human ESCs . In mouse ESCs, LIF promotes self-renewal and pluripotency, but in human cells there is no indication that LIF has the same function. Instead, FGF-basic (FGF-2) and Activin A are used to promote self-renewal and pluripotent potential. Recombinant human LIF is a non-glycosylated protein, containing 181 amino acids, with a molecular weight of 19.9 kDa.

Monocyte Chemotactic Protein 2 (MCP-2), also known as CCL8, is implicated in allergic responses through its ability to activate mast cells, eosinophils, and basophils. MCP-2 is known to signal through several G protein-coupled receptors including, CCR1, CCR2B, and CCR5. Recombinant human MCP-2 is a non-glycosylated protein, containing 76 amino acids, with a molecular weight of 8.9 kDa.

Monocyte Chemotactic Protein 2 (MCP-2), also known as CCL8, is implicated in allergic responses through its ability to activate mast cells, eosinophils, and basophils. MCP-2 is known to signal through several G protein-coupled receptors including, CCR1, CCR2B, and CCR5. Recombinant human MCP-2 is a non-glycosylated protein, containing 76 amino acids, with a molecular weight of 8.9 kDa.

Monocyte Chemotactic Protein 3 (MCP-3), also called CCL7, is produced by macrophages and some tumor cell lines. MCP-3 signals through three different G protein-coupled receptors, CCR1, CCR2, and CCR3. CCL7 chemoattracts monocytes and can regulate macrophage function. Recombinant human MCP-3 is a non-glycosylated protein, containing 76 amino acids, with a molecular weight of 9 kDa.

Monocyte Chemotactic Protein 3 (MCP-3), also called CCL7, is produced by macrophages and some tumor cell lines. MCP-3 signals through three different G protein-coupled receptors, CCR1, CCR2, and CCR3. CCL7 chemoattracts monocytes and can regulate macrophage function. Recombinant human MCP-3 is a non-glycosylated protein, containing 76 amino acids, with a molecular weight of 9 kDa.

Monocyte Chemotactic Protein 4 (MCP-4), also called CCL13, is induced by inflammatory proteins such as IL-1 and TNFα. MCP-4 is a ligand for three different G protein coupled receptors, CCR2, CCR3 and CCR5. MCP-4 activates signaling in monocytes, T lymphocytes, eosinophils and basophils and this signaling is associated with the allergic response. Recombinant human MCP-4 is a non-glycosylated protein, containing 74 amino acids, with a molecular weight of 8.5 kDa.