Other Proteins

Monocyte Chemotactic Protein 4 (MCP-4), also called CCL13, is induced by inflammatory proteins such as IL-1 and TNFα. MCP-4 is a ligand for three different G protein coupled receptors, CCR2, CCR3 and CCR5. MCP-4 activates signaling in monocytes, T lymphocytes, eosinophils and basophils and this signaling is associated with the allergic response. Recombinant human MCP-4 is a non-glycosylated protein, containing 74 amino acids, with a molecular weight of 8.5 kDa.

Monocyte Chemotactic Protein 4 (MCP-4), also called CCL13, is induced by inflammatory proteins such as IL-1 and TNFα. MCP-4 is a ligand for three different G protein coupled receptors, CCR2, CCR3 and CCR5. MCP-4 activates signaling in monocytes, T lymphocytes, eosinophils and basophils and this signaling is associated with the allergic response. Recombinant human MCP-4 is a non-glycosylated protein, containing 74 amino acids, with a molecular weight of 8.5 kDa.

Macrophage Colony Stimulating Factor (M-CSF) is a hematopoietic growth factor produced by a wide variety of cells. M-CSF is known to stimulate differentiation of hematopoietic stem cells to monocyte-macrophage cell populations in culture. M-CSF acts through the CSF receptor 1. Although human M-CSF shows activity on mouse cells, mouse CSF shows no activity on human cells. Recombinant human M-CSF is a disulfide linked homodimer, containing two 159 amino acid chains, with a total molecular weight of 36.8 kDa.

Macrophage Colony Stimulating Factor (M-CSF) is a hematopoietic growth factor produced by a wide variety of cells. M-CSF is known to stimulate differentiation of hematopoietic stem cells to monocyte-macrophage cell populations in culture. M-CSF acts through the CSF receptor 1. Although human M-CSF shows activity on mouse cells, mouse CSF shows no activity on human cells. Recombinant human M-CSF is a disulfide linked homodimer, containing two 159 amino acid chains, with a total molecular weight of 36.8 kDa.

Migration Inhibitory Factor (MIF) is a pro-inflammatory cytokine that acts on fibroblasts by inducing IL-1, IL-8 and MMP expression. MIF stimulates NO production and TNF-α release following IFNγ-activation of macrophages. Recombinant human MIF is a non-glycosylated protein, containing 115 amino acids, with a molecular weight of 12.5 kDa.

Migration Inhibitory Factor (MIF) is a pro-inflammatory cytokine that acts on fibroblasts by inducing IL-1, IL-8 and MMP expression. MIF stimulates NO production and TNF-α release following IFNγ-activation of macrophages. Recombinant human MIF is a non-glycosylated protein, containing 115 amino acids, with a molecular weight of 12.5 kDa.

Migration Inhibitory Factor (MIF) is a pro-inflammatory cytokine that acts on fibroblasts by inducing IL-1, IL-8 and MMP expression. MIF stimulates NO production and TNF-α release following IFNγ-activation of macrophages. Recombinant human MIF is a non-glycosylated protein, containing 115 amino acids, with a molecular weight of 12.5 kDa.

Macrophage Inflammatory Protein-4 (MIP-4), also called CCL18, is a chemokine expressed in the lymph nodes, lungs, placenta and bone marrow. Although the MIP-4’s receptor remains undetermined, MIP-4 is known to act as a chemoattractant for activated and non-activated T cells. Recombinant human MIP-4 is a non-glycosylated protein, containing 69 amino acids, with a molecular weight of 7.8 kDa.

Macrophage Inflammatory Protein-4 (MIP-4), also called CCL18, is a chemokine expressed in the lymph nodes, lungs, placenta and bone marrow. Although the MIP-4’s receptor remains undetermined, MIP-4 is known to act as a chemoattractant for activated and non-activated T cells. Recombinant human MIP-4 is a non-glycosylated protein, containing 69 amino acids, with a molecular weight of 7.8 kDa.