Other Proteins

Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a neurotrophic factor that is closely related to other neurotrophic factors, such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes RET and GFRα1-4, to promote dopamine uptake, survival and differentiation of neurons. Recombinant mouse GDNF is a non-glycosylated homodimer, containing two 135 amino acid chains, with a total molecular weight of 30.2 kDa.

GROα, also known as CXCL1, is a chemokine thought to have mitogenic properties and chemoattract neutrophils. Secreted by macrophages, epithelial cells, neutrophils and melanomas, GROα signals through chemokine receptor, CXCR2, and has been implicated in the processes of spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing. Recombinant mouse GROα is a non-glycosylated protein, containing 72 amino acids, with a molecular weight of 7.8 kDa.

GROα, also known as CXCL1, is a chemokine thought to have mitogenic properties and chemoattract neutrophils. Secreted by macrophages, epithelial cells, neutrophils and melanomas, GROα signals through chemokine receptor, CXCR2, and has been implicated in the processes of spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing. Recombinant mouse GROα is a non-glycosylated protein, containing 72 amino acids, with a molecular weight of 7.8 kDa.

GROα, also known as CXCL1, is a chemokine thought to have mitogenic properties and chemoattract neutrophils. Secreted by macrophages, epithelial cells, neutrophils and melanomas, GROα signals through chemokine receptor, CXCR2, and has been implicated in the processes of spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing. Recombinant mouse GROα is a non-glycosylated protein, containing 72 amino acids, with a molecular weight of 7.8 kDa.

Interferon gamma, IFNγ, is a major immune-modulating molecule produced mainly by T cells and natural killer cells activated by antigens, mitogens or alloantigens. Most immune cells express IFNγ receptors and respond to IFNγ-induced signaling by up-regulating MHC class I expression. Human IFNγ does not show cross-reactivity with mouse. Recombinant mouse IFNγ is a non-glycosylated protein, containing 134 amino acids, with a molecular weight of 15.6 kDa.

Interferon gamma, IFNγ, is a major immune-modulating molecule produced mainly by T cells and natural killer cells activated by antigens, mitogens or alloantigens. Most immune cells express IFNγ receptors and respond to IFNγ-induced signaling by up-regulating MHC class I expression. Human IFNγ does not show cross-reactivity with mouse. Recombinant mouse IFNγ is a non-glycosylated protein, containing 134 amino acids, with a molecular weight of 15.6 kDa.

Insulin-like Growth Factor I, IGF-I, is a growth factor produced in response to growth hormone-stimulated liver and can be found circulating throughout the body and throughout life. IGF-I activates the IGF-I receptor (IGF1R) and the insulin receptor to mediate growth of almost every cell of the body. IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death. Mature human IGF-I is 100% homologous with bovine and porcine proteins. Recombinant mouse IGF-I is a non-glycosylated protein, containing 70 amino acids, with a molecular weight of 7.6 kDa.

Insulin-like Growth Factor I, IGF-I, is a growth factor produced in response to growth hormone-stimulated liver and can be found circulating throughout the body and throughout life. IGF-I activates the IGF-I receptor (IGF1R) and the insulin receptor to mediate growth of almost every cell of the body. IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death. Mature human IGF-I is 100% homologous with bovine and porcine proteins. Recombinant mouse IGF-I is a non-glycosylated protein, containing 70 amino acids, with a molecular weight of 7.6 kDa.

Interleukin-2 (IL-2) is an immuno-modulatory cytokine produced by stimulated T cells. IL-2 signals through the IL-2R receptor to induce proliferation of activated T cells. IL-2 also stimulates proliferation and differentiation of B cells, natural killer cells, monocytes and macrophages. Recombinant mouse IL-2 is a non-glycosylated protein, containing 149 amino acids, with a molecular weight of 17.2 kDa.