Other Proteins

Animal-Free Recombinant Murine Noggin (Legacy Tebubio ref. 167AF-38). Noggin belongs to a group of diffusible proteins that bind to ligands of the TGF-beta family, and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action was critical for proper formation of the head and other dorsal structures. Consequently, noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of noggin in mice results in prenatal death, and a recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant Murine Noggin is a 46.4 kDa disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains.

Animal-Free Recombinant Murine Noggin (Legacy Tebubio ref. 167AF-38). Noggin belongs to a group of diffusible proteins that bind to ligands of the TGF-beta family, and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action was critical for proper formation of the head and other dorsal structures. Consequently, noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of noggin in mice results in prenatal death, and a recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant Murine Noggin is a 46.4 kDa disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains.

Animal-Free Recombinant Murine BD-3 (Legacy Tebubio ref. 167AF-41). Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Murine BD-3 is a 4.6 kDa protein containing 41 amino acid resi

Animal-Free Recombinant Murine BD-3 (Legacy Tebubio ref. 167AF-41). Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Murine BD-3 is a 4.6 kDa protein containing 41 amino acid resi

Human Stem Cell Lineage Differentiation Package (Legacy Tebubio ref. 167HSCLD). The Human Stem Cell Lineage Differentiation Package contains the key components required for the differentiation of stem cells into various cell lineages. The package contains the following three vials: 100ug Human VEGF-165, 100 ug Human TGF-beta 1, 100ug Human/Mouse/Rat Activin A

Human Stem Cell Lineage Differentiation Package Mini (Legacy Tebubio ref. 167HSCLD-M). The Human Stem Cell Lineage Differentiation Package, Mini , contains the key components required for the differentiation of stem cells into various cell lineages. The package contains the following three vials: 10ug Human VEGF-165, 10ug Human TGF-beta 1, 10ug Human/Mouse/Rat Activin A

Human Stem Cell Renewal Package (Legacy Tebubio ref. 167HSCR). The Human Stem Cell Renewal Package contains the key components required to maintain pluripotency and enable self-renewal of iPSCs in cell culture. The package contains the following two vials: 100ug Human FGF-Basic, 100ug Human BMP-4

Human Stem Cell Renewal Package Mini (Legacy Tebubio ref. 167HSCR-M). The Human Stem Cell Renewal Package, Mini, contains the key components required to maintain the self-renewal of your iPSCs in culture. The package contains the following two vials: 10ug Human FGF-basic, 10ug Human BMP-4

Organoid Essentials Package (Legacy Tebubio ref. 167ORE). The Organoid Essentials Package contains the key components required for the development of organoid models in cell culture. The package contains the following five vials: 10ug Mouse Wnt-3a, 100ug Human Noggin, 100ug Human R-Spondin 1, Human FGF-10, 100ug ANimal-Free Human EGF