The Royal Swedish Academy of Sciences has awarded the 2014 Nobel Prize in Chemistry to Eric Betzig (Janelia Farm Research Campus, USA), Stefan W. Hell (MPI Biophysical Chemistry & DKFZ, GE) and William E. Moerner (Stanford University, USA) “for the development of super-resolved fluorescence microscopy”.
2 separate principles rewarded
- STimulated Emission Depletion (STED) microscopy (Stefan Hell)
- Single-molecule microscopy (Eric Betzig & William Moerner)
These fluorescent-based methods allow microscopy to enter into the “nanoworld” (nanoscopy instead of microscopy) and to give Life scientists hyper-resolutive images.
Source
The Nobel Prize in Chemistry 2014 – Eric Betzig, Stefan Hell, William Moerner. Nobelprize.org
Galery of images obtained with the STED microscopy
- Evaluation of AKT activation using STED nanoscopy and mouse anti-AKT pS473 (p/n 200–301–268, Rockland) and ATTO 647N conjugated anti-Mouse IgG. Source: Leica Microsystems.
- Courtesy of Leica Microsystems / Rockland Immunochemicals.
Other high resolutive images obtained with ATTO dyes
