Lysosome and Mitochondria Detection Tools
Ready-to-use reagents for lysosome and mitochondria studies
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Quick & easy detection tools for lysosome and... mitochondria!

Since lysosomal and mitochondrial dysfunction is deeply involved in the onset and progression of neurodegenerative diseases and other disorders, detailed analysis of lysosomes and mitochondria has attracted much attention in elucidating pathological conditions and developing therapeutic agents.

 

Discover four new dyes to study the lysosome:

 

  • Easy & ready-to-use
  • Add & monitor
  • Accurate fluorescence brightness 
  • Specific live cell analysis by co-staining

HeLa cells

Baf.A1: Bafilomycin A1 (lysosomal acidification inhibitor)

 

 

 

Product Name
pHLys Green
pHLys Red
LysoPrime Green
LysoPrime Deep Red
Purpose
pH
pH
Mass
Mass
Fluorescent property
Ex= 488 nm Em= 490-550 nm
Ex= 561 nm Em= 560-650 nm
Ex= 488 nm Em= 500-600 nm
Ex= 633 nm Em= 640-700 nm
Lysosome pH sensitivity
Resistant to pH change
Resistant to pH change
Lysosome specificity
Lysosome retention
Supported devices
Microscope Plate Reader FCM
Microscope Plate Reader FCM (Need G/Y Laser: G: 532 nm, Y: 561 nm)
Microscope Plate Reader FCM
Microscope Plate Reader FCM

pH: detection of accurate pH changes.

Mass : detection of volume changes.

 

 

Order your Lysosome & Mitochondria Detection Dyes now

 

 

Simultaneously detect lysosomal and mitochondrial dysfunction

Co-staining with mtSOX and Lysosomal dyes revealed that CCCP, unlike Antimycin, triggers concurrent lysosomal neutralization and mitochondrial ROS induction.

Explore our wide range of lysosomal and mitochondrial staining and pH detection dyes, and find the kit or reagent that suits your experimental requirements.

 

 

Learn about mitochondria-lysosome contacts in neurogenetic diseases

Reference

  1. Houser MCQ, Mitchell SPC, Sinha P, Lundin B, Berezovska O, Maesako M. Endosome and Lysosome Membrane Properties Functionally Link to γ-Secretase in Live/Intact Cells. Sensors (Basel). 2023;23(5):2651. Published 2023 Feb 28. doi:10.3390/s23052651