PGE2 is a potent lipid mediator involved in maintaining homeostasis but also in the promotion of acute inflammation or immune suppression in chronic inflammation and cancer. Recently, researchers have shown that the activation of the NLRP3 inflammasome in human primary monocyte-derived macrophages is inhibited by PGE2 (1) confirming the role of this lipid is an effective autocrine and paracrine inflammatory modulator maintaining homeostasis during the resolution phase of inflammation.
This paper also proove the importance of having access to simple but robust PGE2 quatitative assays.
Which Prostaglandin E2 (PGE2) Immunoassay kit to choose?
The Prostaglandin E2 (PGE2) Immunoassay kit is designed to quantitatively measure PGE2 present in serum, plasma, urine, saliva, cells, tissue, and tissue culture media samples. This
EIA kit allows for the widest variations in sample size, sensitivity and assay timing of any PGE2 kit:
- Super Fast Kinetics – Same Assay Range at 2 or 16 hours
- Incredible Sensitivity – < 2 pg/mL
- Superior Cross Reactivity to Other Eicosanoids
- Super Low Sample Volume Requirements
- Choice of Incubation Time, Sensitivity, and Sample Volume in a Single Kit
Want to test this kit allowing you to accomplish any PGE2 measurement you may have, do not hesitate to contact us!
References
1.- Sokolowska, M. et al. (2015). The Journal of Immunology, vol. 194 no. 11 5472-5487. doi: 10.4049/jimmunol.1401343.
