Cell Line

Please note this product may be subject to fees, we invite you to contact your local office.BCMA Knockout RPMI-8226 Cell Line is an RPMI-8226 cell line in which BCMA (B-Cell Maturation Antigen, or CD269) has been genetically removed from RPMi-8226 cells using CRISPR/Cas9 genome editing by RNP (ribonucleoprotein) electroporation. This cell line has been validated by genome sequencing and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. TROP2 Knockout MCF7 Cell Line is an MCF7 breast cancer cell line in which human TROP2 (Trophoblast cell-surface antigen 2 or TACSTD2) has been genetically removed using CRISPR/Cas9 genome editing with a lentivirus encoding CRISPR/Cas9 gene and sgRNA (single guide RNA) targeting human TROP2. This cell line has been validated by genomic sequencing and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. EGFR Knockout A549 Cell Line is an A549 lung cancer cell line in which human EGFR (epidermal growth factor receptor) has been genetically removed using CRISPR/Cas9 genome editing with a lentivirus encoding CRISPR/Cas9 gene and sgRNA (single guide RNA) targeting human EGFR. This cell line has been validated by genomic sequencing and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. The DLL4 CHO Cell Line is a CHO-K1 cell line expressing human delta-like 4 (DLL4) gene (accession number NM_019074.4) under the control of the cytomegalovirus (CMV) promoter. This cell line was generated by lentiviral transduction followed by puromycin selection and limiting dilution. Individual clones were screened based on DLL4 expression by flow cytometry to obtain this DLL4 expressing cell line.

Please note this product may be subject to fees, we invite you to contact your local office. BCMA Knockout MM.1S Cell Line is an MM.1S B lymphoblast cell line in which BCMA (B-Cell Maturation Antigen, or CD269) has been genetically removed using CRISPR/Cas9 genome editing. This cell line has been validated by genome sequencing and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. eGFP/Firefly Luciferase BCMA Knockout RPMI 8226 Cell Line is a RPMI 8226 cell Line constitutively expressing firefly (Photinus pyralis) luciferase and the enhanced GFP (eGFP) cassette under the control of a CMV promoter. BCMA (B-Cell Maturation Antigen, or CD269) expression has been genetically removed using CRISPR/Cas9 genome editing. This cell line was generated by using the eGFP/Firefly Luciferase Lentivirus (BPS Bioscience #79980). This cell line has been validated by genome sequencing, flow cytometry and luciferase activity measurement.

Please note this product may be subject to fees, we invite you to contact your local office. Firefly Luciferase BCMA Knockout RPMI-8226 Cell Line is a RPMI-8226 cell Line constitutively expressing firefly (Photinus pyralis) luciferase under the control of a CMV promoter, and in which BCMA (B-Cell Maturation Antigen, or CD269) has been genetically removed using CRISPR/Cas9 genome editing. This cell line was generated by using Firefly Luciferase Lentivirus (BPS Bioscience #79692). This cell line has been validated by genome sequencing, flow cytometry and luciferase activity measurement.

Please note this product may be subject to fees, we invite you to contact your local office. PARP1 Knockout MCF7 Cell Line is an MCF7 breast cancer cell line in which human PARP1 (Poly-(ADP-ribose) Polymerase 1) has been genetically removed using CRISPR/Cas9 genome editing. This cell line has been validated by genomic sequencing and Western Blot.

Please note this product may be subject to fees, we invite you to contact your local office. PARG Knockout MCF7 Cell Line is an MCF7 breast cancer cell line in which human PARG (Poly ADP-ribose glycohydrolase) has been genetically removed using CRISPR/Cas9 genome editing. This cell line has been validated by genomic sequencing and Western Blot.