Labelling

Intermediate to forming more complex fluorescein/rhodamine derivatives? No other information found online

2,7′-Dichlorofluorescein ) is a fluorescent dye that finds extensive application in diverse scientific research endeavors. It serves as a valuable tool for researchers due to its versatile nature, enabling the detection of reactive oxygen species (ROS), exploration of enzyme activity, and analysis of cell signaling pathways. Moreover, DCF proves instrumental in numerous laboratory experiments, encompassing cell culture, protein purification, and bioassays. The utilization of 2′,7′-Dichlorofluorescein spans a wide array of scientific research applications. It plays a pivotal role in ROS detection, study of enzyme activity, and analysis of cell signaling pathways. Additionally, 2′,7′-Dichlorofluorescein serves as a valuable tool for detecting DNA damage, studying apoptosis, and quantifying intracellular calcium levels. Upon light exposure, it emits a vibrant orange-red fluorescence, facilitating the identification of ROS and other molecules within cells. Moreover, it enables the detectio

AMCA-PEG4-NHS ester is a AMCA dye linker containing a NHS ester group and a hydrophilic PEG spacer arm. The NHS ester allows the dye to react with primary amines and the hydrophilic PEG spacer arm increases water solubility as well as membrane permability. This dye is used for protein and peptide labeing. The structure is similar to commercial AMCA-X-SE with better solubility and conjugation efficiency. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 546 Alkyne is a bright, orange-fluorescent dye that reacts with terminal azide via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. It is a popular labeling dye used in Click Chemistry reactions. BP Fluor 546 Alkyne is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates which are often used for generating stable signals in imaging and flow cytometry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

9-azido-9-deoxy-N-acetylneuraminic acid (9AzNeu5Ac), a Neu5Ac analogue with the substitution of 9-hydroxyl group with an azide, is a great click chemistry reagent could be metabolized and incorporated into sialoglycans in living cells and mice. It will react with the DBCO or other alkyne group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. Metabolic labeling of glycans with unnatural sialic acid analogues has emerged as an invaluable tool for studying sialic acid biology. The incorporated sialic acid analogue, 9AzNeu5Ac, enable visualization the cell-surface sialoglycans and glycoproteomic profiling by click-labeling with fluorophores and affinity tags, respectively. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 800 Azide is a conceptually new class of sterically shielded NIR cyanine heptamethine dye with emission wavelengths >740 nm. This dye contains two shielding PEG arms directly over both faces of the heptamethine fluorochrome blocking any undesired bimolecular association processes, resulting in a significant increase in fluorescence brightness. BP Fluor 800 Azide can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 800 DBCO is a conceptually new class of sterically shielded NIR cyanine heptamethine dye with emission wavelengths >740 nm. This dye contains two shielding PEG arms directly over both faces of the heptamethine fluorochrome blocking any undesired bimolecular association processes, resulting in a significant increase in fluorescence brightness. BP Fluor 800 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions and reacts with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 546 (Alexa Fluor 546 equivalent; AF546) NHS Ester is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It reacts with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules, which are often used for generating stable signals in imaging and flow cytometry. It can be used with the 488 nm and 532 nm laser lines. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 680 (Alexa Flour 680 Equivalent) NHS Ester is a bright and photostable fluorescent dye with an excitation peak at 681 nm and an emission peak at 704 nm. It is spectrally identical to Alexa Fluor® 680 and IRDye® 680RD. It reacts with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules and is often used for small animal imaging, cytometry, western blot, etc. BP Fluor 680 molecules can be conjugated to proteins at high molar ratios without significant self-quenching. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.