Nucleic Acids

CleanCap® Reagent AG is TriLink’s proprietary co-transcriptional capping reagent for in vitro transcription of 5’ capped mRNA resulting in a Cap 1 structure. CleanCap has shown to provide up to 98% capping efficiency. PLEASE NOTE: TriLink recommends trying both CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) whenever possible. CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) require an AG initiator. To learn more, please review the Product Insert below. Our CleanCap reagents are available in “Research Use” grade as well as GMP-grade “For Further Processing.” GMP product is manufactured in accordance with ISO 9001:2015 and Quality Standards as defined in a GMP Quality Agreement, and must be further processed by the client.

CleanCap® Reagent AG is TriLink’s proprietary co-transcriptional capping reagent for in vitro transcription of 5’ capped mRNA resulting in a Cap 1 structure. CleanCap has shown to provide up to 98% capping efficiency. PLEASE NOTE: TriLink recommends trying both CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) whenever possible. CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) require an AG initiator. To learn more, please review the Product Insert below. Our CleanCap reagents are available in “Research Use” grade as well as GMP-grade “For Further Processing.” GMP product is manufactured in accordance with ISO 9001:2015 and Quality Standards as defined in a GMP Quality Agreement, and must be further processed by the client.

CleanCap® Reagent AG is TriLink’s proprietary co-transcriptional capping reagent for in vitro transcription of 5’ capped mRNA resulting in a Cap 1 structure. CleanCap has shown to provide up to 98% capping efficiency. PLEASE NOTE: TriLink recommends trying both CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) whenever possible. CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) require an AG initiator. To learn more, please review the Product Insert below. Our CleanCap reagents are available in “Research Use” grade as well as GMP-grade “For Further Processing.” GMP product is manufactured in accordance with ISO 9001:2015 and Quality Standards as defined in a GMP Quality Agreement, and must be further processed by the client.

CleanCap® Reagent AG is TriLink’s proprietary co-transcriptional capping reagent for in vitro transcription of 5’ capped mRNA resulting in a Cap 1 structure. CleanCap has shown to provide up to 98% capping efficiency. PLEASE NOTE: TriLink recommends trying both CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) whenever possible. CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) require an AG initiator. To learn more, please review the Product Insert below. Our CleanCap reagents are available in “Research Use” grade as well as GMP-grade “For Further Processing.” GMP product is manufactured in accordance with ISO 9001:2015 and Quality Standards as defined in a GMP Quality Agreement, and must be further processed by the client.

CleanCap® Reagent AU is designed for the co-transcriptional capping of mRNA to produce an mRNA with naturally occurring Cap 1. CleanCap Reagent AU was specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN). The positive sense strand genomes of these viruses start with a 5’ AU structure. Cap 1 mRNAs have superior in vivo activity compared to Cap 0 mRNA produced by legacy co-transcriptional capping methods like anti-reverse cap analog (ARCA). PLEASE NOTE: CleanCap Reagent AU requires an AU initiator. To learn more, please review the Product Insert below.

CleanCap® Reagent AU is designed for the co-transcriptional capping of mRNA to produce an mRNA with naturally occurring Cap 1. CleanCap Reagent AU was specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN). The positive sense strand genomes of these viruses start with a 5’ AU structure. Cap 1 mRNAs have superior in vivo activity compared to Cap 0 mRNA produced by legacy co-transcriptional capping methods like anti-reverse cap analog (ARCA). PLEASE NOTE: CleanCap Reagent AU requires an AU initiator. To learn more, please review the Product Insert below.

CleanCap® Reagent AU is designed for the co-transcriptional capping of mRNA to produce an mRNA with naturally occurring Cap 1. CleanCap Reagent AU was specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN). The positive sense strand genomes of these viruses start with a 5’ AU structure. Cap 1 mRNAs have superior in vivo activity compared to Cap 0 mRNA produced by legacy co-transcriptional capping methods like anti-reverse cap analog (ARCA). PLEASE NOTE: CleanCap Reagent AU requires an AU initiator. To learn more, please review the Product Insert below.

CleanCap® Reagent AU is designed for the co-transcriptional capping of mRNA to produce an mRNA with naturally occurring Cap 1. CleanCap Reagent AU was specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN). The positive sense strand genomes of these viruses start with a 5’ AU structure. Cap 1 mRNAs have superior in vivo activity compared to Cap 0 mRNA produced by legacy co-transcriptional capping methods like anti-reverse cap analog (ARCA). PLEASE NOTE: CleanCap Reagent AU requires an AU initiator. To learn more, please review the Product Insert below.

CleanCap® Reagent AG (3' OMe) is TriLink’s proprietary co-transcriptional capping reagent for in vitro transcription of 5’ capped mRNA resulting in a Cap 1 structure. CleanCap has shown to provide up to 98% capping efficiency. CleanCap Reagent AG (3' OMe) includes the 5' N7-Methyl-3'-O-Methylguanosine commonly found in mRNA capped using ARCA, whereas CleanCap Reagent AG has a naturally occurring 5' N7-Methylguanosine structure. PLEASE NOTE: TriLink recommends trying both CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) whenever possible. CleanCap Reagent AG and CleanCap Reagent AG (3’ OMe) require an AG initiator. To learn more, please review the Product Insert below. Our CleanCap reagents are available in “Research Use” grade as well as GMP-grade “For Further Processing.” GMP product is manufactured in accordance with ISO 9001:2015 and Quality Standards as defined in a GMP Quality Agreement, and must be further processed by the client.