Enzymes

Human endoplasmic reticulumto- nucleus signaling 1 (ERN1), also known as inositol-requiring protein 1 (IRE1), GenBank Accession No. NM_001433, a.a. 468-977 (end) MW = 87 kDa, expressed in a baculovirus-infected Sf9 insect cell expression system.

Human cyclin-dependent kinase 9 (CDK9), also known as C-2K and cell division protein kinase 9, complexed with human cyclin T1 (CCNT1, CycT1), GenBank Accession Nos. NM_001261 (CDK9) and NM_001240 (CyclinT1), a.a. 2- 372(end) (CDK9) and a.a. 2-726(end) (CyclinT1) each with N-terminal GST-tags, co-expressed in a baculovirus-infected Sf9 cell expression system. MW = 69 kDa (CDK9) and 107 kDa (CyclinT1).

Human TTBK1 protein, also known as Tau-tubulin kinase-1, GenBank Accession No. NM_032538, a.a. 1-479, with N-terminal GST-tag and C-terminal His-tag. MW = 81 kDa, expressed in Sf9 cells via a baculovirus expression system.

Human Casein Kinase 1α1, also known as CSNK1A1 (GenBank Accession NM_001892, (no tag). a.a 2-337 (end). Expressed in an insect Sf9 cell expression system. MW=65 kDa.

Human EGFR T790M L858R (GenBank Accession No. NM_005228), a.a. 668-1210 with substitutions of Threonine790 to Methionine and Leucine858 to Arginine and an N-terminal GST-tag, MW= 88 kDa, expressed in a baculovirus expression system.

Human EGFR T790M, C797S, L858R (GenBank Accession No. NM_005228), (a.a. 668-1210) with Nterminal GST tag, MW = 88 kDa, expressed in baculovirus expression system.

Human TEK tyrosine kinase, endothelial, also known as Tie2, (GenBank Accession No. NM_000459) a.a. 771-1124(end) with N-terminal GST-tag, MW= 66 kDa, expressed in baculovirus infected Sf9 cell expression system.

Human RIPK1, also known as RCK and MAP3K19, GenBank Accession No. NM_003804, a.a. 1-327, with N-terminal GST-tag, MW=63 kDa, expressed in a Baculovirus-infected Sf9 cell expression system.

Recombinant human ROR1 (GenBank Accession No. NM_005012), a.a. 429-end, with N-terminal GST-tag, MW 82 kDa, expressed in Sf9 insect cells via a baculovirus expression system.