Enzymes

Human PDE3B (GenBank Accession No. NM_000922), a.a. 592-end, with N-terminal GST-tag, MW = 86 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Human PDE3A (GenBank Accession No. NM_000921), a.a. 669-1141(end) with N-terminal His-GST-tag, MW = 82 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Mouse PDE3A (GenBank Accession No. NM_018779), amino acids 484-1141 end), with N-terminal GST tag, MW = 100 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Human PDE4A10, also known as PDE4A protein isoform 6, transcript variant 3 (GenBank Accession No. NM_001111309), a.a. 2-825(end) with N-terminal GST-tag, MW= 117 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Human PDE4A4B, also known as PDE4A isoform 1 (GenBank Accession No. NM_001111307), a.a. (2-end) with N-terminal GST-tag, MW= 124 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Recombinant human full lenght PDE4A (Phosphodiesterase 4A) isoform 4, amino acids 1-647. This construct contains an N-terminal GST-tag, followed by an His-Tag (6xHis) and a thrombin cleavage site. This protein was affinity purified.

Human PDE4B1 (GenBank Accession No. NM_001037341), full length with N-terminal GST-tag, MW= 109 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Human PDE4B2 (GenBank Accession No. NM_001037339), full length, with N-terminal GST-tag and C-terminal His-tag, MW=91.2 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Human PDE4C1 (GenBank Accession No. NM_000923), full length, with N-terminal GST-tag, MW=106 kDa, expressed in a Baculovirus infected Sf9 cell expression system.