Cells

Human Peripheral Blood Mononuclear Cells (PBMCs) are utilized as source material for isolating lymphocytes (T cells, B cells and NK cells) and monocytes in research and across fields such as immunology, immuno-oncology, and cell and gene therapies. All PBMCs are isolated through Ficoll density gradient separation from freshly obtained leukapheresis ACD-A packs and directly cryopreserved. Our offerings encompass distinct options tailored to meet diverse research requirements. These options include PBMCs sourced from our existing inventory, which are further categorized into three groups, each offering unique features and application possibilities. We also provide PBMCs from prospective collections, ensuring flexibility and suitability for various research needs. PBMC-discovery includes donor information (e.g., smoking status, chronic diseases, allergies, medications), serological tests, mycoplasma/bacterial/fungal contamination, HLA Class I and II, FCGR3A Polymorphisms, pre-freeze hema

Human B cells have been isolated from mononuclear cells through either positive or negative selection using immunomagnetic cell separation techniques. In positive selection, the targeted isolation of CD19+ B cells was performed, while in negative selection, other cell types were removed to obtain pure CD19+ B cells. These differentiated procedures provide our B-cell products with high specificity. Derived from mononuclear cells, CD19+ B cells play a central role in the immune response by responding to potential threats through the release of antibodies specific to antigens such as bacteria and viruses. The expression of CD19+ facilitates the identification of these B-cells

Human B cells have been isolated from mononuclear cells through either positive or negative selection using immunomagnetic cell separation techniques. In positive selection, the targeted isolation of CD19+ B cells was performed, while in negative selection, other cell types were removed to obtain pure CD19+ B cells. These differentiated procedures provide our B-cell products with high specificity. Derived from mononuclear cells, CD19+ B cells play a central role in the immune response by responding to potential threats through the release of antibodies specific to antigens such as bacteria and viruses. The expression of CD19+ facilitates the identification of these B-cells

Human CD14+ T cells, obtained from mononuclear cells, are isolated through either negative or positive selection using immunogenetic cell separation techniques. These cells play a crucial role in the immune response against infections and are valuable for the investigation and diagnosis of immune reactions, particularly in infections and inflammation. Their ability to act as detectors for bacterial presence and respond to lipopolysaccharides (LPS) underscores their significance in combating infections through phagocytosis, as well as in maintaining immune balance and defending against microbial threats.

Human CD14+ T cells, obtained from mononuclear cells, are isolated through either negative or positive selection using immunogenetic cell separation techniques. These cells play a crucial role in the immune response against infections and are valuable for the investigation and diagnosis of immune reactions, particularly in infections and inflammation. Their ability to act as detectors for bacterial presence and respond to lipopolysaccharides (LPS) underscores their significance in combating infections through phagocytosis, as well as in maintaining immune balance and defending against microbial threats.

Human Natural Killer cells (NK cells) constitute a lymphocytic subset of the immune system and play a crucial role in immunological surveillance and host defense. Their significance spans across various areas such as bone marrow transplantation, cancer, pregnancy, autoimmune diseases, viral infections, and increasingly in adaptive immunity. The common identification of NK cells is achieved through the surface marker CD56. These cells are isolated using negative or positive selection through immunomagnetic cell separation procedures.

Human Natural Killer cells (NK cells) constitute a lymphocytic subset of the immune system and play a crucial role in immunological surveillance and host defense. Their significance spans across various areas such as bone marrow transplantation, cancer, pregnancy, autoimmune diseases, viral infections, and increasingly in adaptive immunity. The common identification of NK cells is achieved through the surface marker CD56. These cells are isolated using negative or positive selection through immunomagnetic cell separation procedures.

Human Isolated T cells, including CD3+ pan-T cells, CD4+ and CD8+ subgroups, have been obtained through immunomagnetic cell separation techniques employing positive or negative selection from mononuclear cells. These differentiated procedures ensure the precise isolation of the intended T-cell groups. CD4+ T cells play a role in coordinating immune responses, while CD8+ T cells exert a cytotoxic function.

Human Isolated T cells, including CD3+ pan-T cells, CD4+ and CD8+ subgroups, have been obtained through immunomagnetic cell separation techniques employing positive or negative selection from mononuclear cells. These differentiated procedures ensure the precise isolation of the intended T-cell groups. CD4+ T cells play a role in coordinating immune responses, while CD8+ T cells exert a cytotoxic function.