Lipids & Polymers

DSPE-PEG-SH, MW 5,000 is a polyPEG attached DSPE molecule. The lipid tails allow formation of lipid bilayer in water and can be used to solubilize hydrophobic drugs while the hydrophilic core can encapsulate therapeutic agents, such as nuclein acid (mRNA/DNA), protein or peptide. Reagent grade, for research purpose.

DSPE-PEG-Vinylsulfone, MW 1,000 is a self-assembling PEG reagent which forms lipid bilayer. The amphiphilic polymer can be used to prepare liposome for delivering therapeutics, such as nucleic acid (mRNA/DNA) or protein. The vinyl sulfone moiety is reactive with cysteine or other thiol molecule via thiol-ene chemistry. Reagent grade, for research purpose.

DSPE-PEG-Vinylsulfone, MW 2,000 is a phospholipid PEG which can self-assemble to form lipid bilayer in water. The polymer can be used to encapsulate therapeutics, such as nucleic acid (mRNA/DNA) or protein, in drug delivery system. The vinyl sulfone is reactive with thiol molecule via thiol-ene reaction for bioconjugation. Reagent grade, for research purpose.

DSPE-PEG-Vinylsulfone, MW 3,400 is a thiol reactive PEG lipid. The polymer can self-assemble spontaneously in aqueous solution to form lipid bilayer and be used to prepare nanoparticles/liposomes for drug delivery, for example mRNA vaccine or DNA vaccine. Reagent grade, for research purpose.

DSPE-PEG-Vinylsulfone, MW 5,000 is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine. Reagent grade, for research purpose.

DSPE-PEG-NHS, MW 600 is a phospholipid PEG which can react with protein/peptide or other amine molecule. The polymer forms lipid bilayer in an aquoeus solution and can be used to prepare liposomes for drug delivery applications, such as mRNA vaccine or immunotherapy. Reagent grade, for research purpose.

Sulfo DBCO-PEG4-TFP ester is a short PEG linker featuring a DBCO group, a sulfate, and a TFP ester. DBCO is a click chemistry handle which efficiently reacts with azide groups on target molecules, while the TFP is a good leaving group which is readily displaced by nucleophiles such as amines. Finally, the sulfate group is able to increase the solubility of this linker.

Pentacosadiynoic acid-MPEG, MW 2,000 is a photo responsive PEG reagent. The amphiphile polymer can self-assemble in aqueous solution to form micelles which can encapsulate drug. The acetylene moieties of the fatty acid can be photo-polymerized by UV radiation at 254 nm wavelength. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Pentacosadiynoic acid-MPEG, MW 5,000 is a UV-responsive amphiphilic PEG polymer. The polymer is a self-assembling reagent which forms micelles in water and can be used to prepare drug-loaded nanoparticles. The unsaturated fatty acid can be photopolymerized in the presence of 254nm UV light to yield a crosslinked micelles. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.