Lipids

1-Stearoyl-2-oleoyl-sn-glycero-3-phosphoethanol (SOPEth) is a form of phosphatidylethanol (PEth) which is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phosphlipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes and is one of the longest-lived circulating EtOH metabolite yet identified. SOPEth is a one of five most abundant naturally ocurring PEth species.

1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphoethol (PAPEth) is a form of phosphaytidylethanol (PEth) which is formed primarily by transphosphatidylation of phosphatyidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes and is one of the longest-lived circulating EtOH metabolite yet identified. d5-PAPEth has fully deuterated ethanol headgroup and is an analog of one of five most abundant naturally occurring PEth species.

1-Oleoyl-sn-glycero-3-phosphoethanol (18:1 LysoPEth) aka lysophosphatidylethanol is a lysophospholipid formed by PLA2 hydrolysis of the ethanol biomarker phosphatidylethanol (PEth). Many bioactive lysophospholipid compounds exhibit pleiomorphic effects on numerous cell lineages including ovarian cancer cells as described in many publications.

Phosphatidylethanol (PEth) is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phosphlipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes and is one of the longest-lived circulating EtOH metabolite yet identified. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanol-d5 (d5-PLPEth) has a fully deuterated ethanol headgroup and can be used as a mass spectrometry standard.

Phosphatidylethanol (PEth) is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phosphlipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes and is one of the longest-lived circulating EtOH metabolite yet identified. 1-Stearoyl-2-oleoyl-sn-glycero-3-phosphoethanol-d5 (d5-SOPEth) has a fully deuterated ethanol headgroup and can be used as a mass spectrometry standard.

Phosphatidylethanol (PEth) is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phosphlipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes and is one of the longest-lived circulating EtOH metabolite yet identified. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanol-d5 (d5-SLPEth) has a fully deuterated ethanol headgroup and can be used as a mass spectrometry standard.

Phosphaytidylethanol (PEth) is formed primarily by transphosphatidylation of phosphatyidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes and is one of the longest-lived circulating EtOH metabolite yet identified. 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphoethol-d5 (d5-PAPEth) is fully deuterated on the ethanol headgroup and is an analog of one of the five most abundant naturally occurring PEth species.

Biotin-Labled Phosphatidylethanol (Biotin-PEth) can be used to build biological assays testing for serum and in vitro PEth levels. PEth is formed primarily in the liver by transphosphatidylation of phosphatidylcholine (PC) by phospholipase D. PEth is associated with lipoprotein particles VLDL and HDL. PEth-containg HDL/protein complexes may protect against atherogenesis by promoting vascular endothelial growth factor secretion by smooth muscle cells and endothelium. Most PEth (about 75%) is incorporated into erythrocyte membranes and is the longest-lived circulating ethanol metabolite yet identified.

Biotin-Phosphatidylethanol (Biotin-PEth) can be used to build biological assays testing for serum and in vitro PEth levels. PEth is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes and is one of the longest-lived circulating ethanol metabolite yet identified.