Lipids

PI(3)P diC8 (Phosphatidylinositol 3-phosphate diC8) ammonium salt is a synthetic purified dioctanoyl PI(3)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.Featured in Publications1) Mari M. E. Macia et al. (2001). "Role of the FYVE finger and the RUN domain for the subcellular localization of Rabip4." J Biol Chem 276(45): 42501-8.2) Kim S. A. G. S. Taylor et al. (2002). "Myotubularin and MTMR2 phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease." J Biol Chem 277(6): 4526-31.3) Koharudin L. M. W. Furey et al. (2009). "The phox domain of sorting nexin 5

PI(3)P diC16 (Phosphatidylinositol 3-phosphate diC16) is a synthetic purified dipalmitoyl PI(3)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.Product Keywords: Dipalmitoyl Phosphatidylinositol 3-phosphate PtdIns(3)P C16 PI(3)P C16 or PI3PBulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1) Sbrissa D. O. C. Ikonomov et al. (2000). "PIKfyve lipid kinase is a protein kinase: downregulation of 5'- phosphoinositide product formation by autophosphorylation [In Process Citation]." Biochemistry 39(51): 15980-9.2) Kutateladze T. G. D

PI(3 4)P2 diC4 (Phosphatidylinositol 3 4-bisphosphate diC4) is a synthetic purified dibutanoyl PI(3 4)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4-bisphosphate (PI(3 4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP TPTE etc.). PI(3 4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.Product Keywords: Dibutanoyl Phosphatidylinositol 3 4-bisphosphate PtdIns(3 4)P2 C4 PI(3 4)P2 C4 or PI34P2.Bulk discounts available please email echelon@echelon-inc.com for details.Publications Powered by Bioz See more details on Bioz1. Fernandes F. et al. (2011). "Phosphoinositides direct equine infectious anemia virus gag trafficking and release." Traffic 12(4): 438-451.2. Stampoulis P. T. Ueda et

PI(3 4)P2 diC8 (Phosphatidylinositol 3 4-bisphosphate diC8) is a synthetic purified dioctanoyl PI(3 4)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4-bisphosphate (PI(3 4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP TPTE etc.). PI(3 4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.Product Keywords: Dioctanoyl Phosphatidylinositol 3 4-bisphosphate PtdIns(3 4)P2 C8 PI(3 4)P2 C8 or PI34P2.Bulk discounts available please email echelon@echelon-inc.com for details.Publication Powered by Bioz See more details on Bioz1. Elge S. C. Brearley et al. (2001). "An Arabidopsis inositol phospholipid kinase strongly expressed in procambial cells: synthesis of PtdIns(4 5)P2 and PtdIns(3 4 5)P3

PI(3 4)P2 diC16 (Phosphatidylinositol 3 4-bisphosphate diC16) is a synthetic purified dipalmitoyl PI(3 4)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4-bisphosphate (PI(3 4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP TPTE etc.). PI(3 4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.Product Keywords: Dipalmitoyl Phosphatidylinositol 3 4-bisphosphate PtdIns(3 4)P2 (16:0/16:0) PI(3 4)P2 C16 or PI34P2.Bulk discounts available please email echelon@echelon-inc.com for details.Publication Powered by Bioz See more details on Bioz1. Dowler S. R. A. Currie et al. (1999). "DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides." Biochem J 342(Pt 1): 7-12.2. Karathanassis D.

PI(3 4)P2 diC16 (Phosphatidylinositol 3 4-bisphosphate diC16) ammonium salt is a synthetic dipalmitoyl PI(3 4)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4-bisphosphate (PI(3 4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP TPTE etc.). PI(3 4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.Solubility70:28:4 CHCl3:MeOH:H2O 0.5 mg/mlFeatured in Publications1) Dowler S. R. A. Currie et al. (1999). "DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides." Biochem J 342(Pt 1): 7-12.2) Karathanassis D. R. V. Stahelin et al. (2002). "Binding of the PX domain of p47(phox) to phosphatidylinositol 3 4- bisphosphate and phosphatidic acid is masked by an intramolecular interaction

PI(3 5)P2 diC4 (Phosphatidylinositol 3 5-bisphosphate diC4) is a synthetic purified dibutanoyl PI(3 5)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 5-bisphosphate is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3 5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease).Product Keywords: Dibutanoyl Phosphatidylinositol 3 5-bisphosphate PtdIns(3 5)P2 C4 PI(3 5)P2Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1. He F. M. Mao et al. (2004). "Enhancement of phototransduction g protein-effector interactions by phosphoinositides." J Biol Chem 279(10): 8986-

PI(3 5)P2 diC8 (Phosphatidylinositol 3 5-bisphosphate diC8) is a synthetic purified dioctanoyl PI(3 5)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 5-bisphosphate is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3 5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease).Product Keywords: Dioctanoyl Phosphatidylinositol 3 5-bisphosphate PtdIns(3 5)P2 (8:0/8:0) PI(3 5)P2 C8Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1. Marcus S. L. M. R. Wenk et al. (2001). "A synaptojanin-homologous region of Salmonella typhimurium SigD is essential for inositol pho

PI(3 5)P2 diC16 9Phosphatidylinositol 3 5-bisphosphate diC16) is a synthetic purified dipalmitoyl PI(3 5)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 5-bisphosphate is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3 5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease).Product Keywords: Dipalmitoyl Phosphatidylinositol 3 5-bisphosphate PtdIns(3 5)P2 (16:0/16:0) PI(3 5)P2 C16Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1. Ikonomov O. C. D. Sbrissa et al. (2002). "Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role