Lipids

GroPI(3 4 5)P3 (Glycerophosphoinositol 3 4 5-triphosphate) is a synthetic phosphoinositide without acyl chains on the 1- & 2-positions of the glycerol.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2. Glycerophosphoinositol 3 4 5-triphosphate (GroPIP3) is missing the acyl chains from the 1- & 2-positions of the glycerol.

PI(3 4 5)P3 diC4 (Phosphatidylinositol 3 4 5-trisphosphate diC4) is a synthetic purified dibutanoyl PI(3 4 5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: Dibutanoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 (4:0/4:0) PI(3 4 5)P3 (4:0/4:0) or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1. Thapar R. A. E. Karnoub et al. (2002). "Structural and biophysi

PI(3 4 5)P3 diC8 (Phosphatidylinositol 3 4 5-trisphosphate diC8) is a synthetic purified dioctanoyl PI(3 4 5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: Dioctanoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 (8:0/8:0) PI(3 4 5)P3 C8 or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1. Paternotte N. J. Zhang et al. (2005). "SHIP2 interaction with the cyto

PI(3 4 5)P3 diC16 (Phosphatidylinositol 3 4 5-trisphosphate diC16) is a synthetic purified dipalmitoyl PI(3 4 5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: Dipalmitoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 C16 PI(3 4 5)P3 C16 or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1) Weiner O. D. P. O. Neilsen et al. (2002). "A PtdInsP(3)- and Rho GTPas

PI(3 4 5)P3 diC16 (Phosphatidylinositol 3 4 5-trisphosphate diC16) ammonium salt is a synthetic purified dipalmitoyl PI(3 4 5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Featured in PublicationsAJP - Renal Physiology Apr 2006AJP - Lung Cellular and Molecular Physiol Mar 2006Product Keywords: Dipalmitoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 C16 PI(3 4 5)P3 C16 or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.

PI(3 4 5)P3 (D-myo-Phosphatidylinositol 3 4 5-trisphosphate) 17:0/16:0 is a synthetic PI(3 4 5)P3 analog with an unnatural C17 acyl chain at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2. Phosphatidylinositol 3 4 5-trisphosphate 17:0/16:0 is a synthetic PI(3 4 5)P3 analog with an unnatural C17 acyl chain at the sn-1 position. Product Keywords: Dipalmitoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 PI(3 4 5)P3 (17:0/16:0) or PIP3Bulk discounts a

PI(3 4 5)P3 (Phosphatidylinositol 3 4 5-trisphosphate) 18:0/20:4 is a synthetic purified PI(3 4 5)P3 with stearoyl and arachidonoyl acyl groups.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: 1-Stearoyl-2-arachidonoyl-phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 (18:0/20:4) PI(3 4 5)P3 (18:0/20:4) or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz

PtdIns(3 4 5)P3 3-methylenephosphonate diC8 (3C-PtdIns(3 4 5)P3 diC8) is a synthetic PI(3 4 5)P3 analog in which the 3-phosphate bond has been rendered metabolically stable as a methylenephosphonate. P-3C908 increases sodium transport across monolayers of cells A6 through activation of GLUT4. Powered by Bioz See more details on Bioz

PtdIns(3 4 5)P3 3-methylenephosphonate diC16 (3C-PtdIns(3 4 5)P3 diC16) is a synthetic PI(3 4 5)P3 analog in which the 3-phosphate bond has been rendered metabolically stable as a methylenephosphonate. P-3C916 increases sodium transport across monolayers of cells A6 through activation of GLUT4.