DNA & Clones

Purity is suitable for all molecular biology applications. Free of RNA, protein, nucleotide, RNase, and DNase contamination. pUC plasmids are virtually pure supercoiled form, containing minimal nicked plasmid and chromosomal DNA contamination. M13 double stranded plasmids are further purified to remove all residual single stranded phage DNA, which can interfere with transformations. M13mp18 ssDNA and M13mp19 ssDNA are useful for DNA origami applications. pUC plasmids and M13 ssDNA are supplied in TE buffer at 1.0 ug/ul concentration. M13 dsDNA plasmid is supplied at 0.50 ug/ul concentration.

The ANPRA/Aequorin expression vector is designed to co-express human atrial natriuretic peptide receptor A (ANPRA, also called natriuretic peptide receptor A/guanylate cyclase A) and jellyfish (Aequorea victoria) Aequorin in mammalian cells.

The CNGA2 expression vector is designed to express human cyclic nucleotide-gated cation channel 2 (CNGA2) in mammalian cells.

Please note this product may be subject to fees, we invite you to contact your local office. The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T-cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. PD-1 ligands are found on most cancers, and the PD-1:PD-L1/2 interaction inhibits T-cell activity and enables cancer cells to escape immune surveillance. The PD-1:PD-L1/2 pathway is also involved in regulating autoimmune responses, making these proteins promising therapeutic targets for a number of cancers, as well as multiple sclerosis, arthritis, lupus, and type I diabetes. <br />This sgRNA (single guide RNA) pool is designed for use with the CRISPR Synergistic Activation Mediator (SAM) system to induce transcriptional activation and expression of any gene of interest. CRISPRa (SAM) cells stably express a mutated dCas9 (Streptococcus pyogenes CRISPR associated protein 9), lacking any endonuclease activity, fused with VP64, a

Activated DNA for PARP assay, for use with BPS's assay kits for PARPs 1, 2, 3, and 6. PARP1 Chemiluminescent Assay Kit, #80551 ; PARP2 Chemiluminescent Assay Kit, #80552; PARP3 Chemiluminescent Assay Kit, #80553; PARP6 Chemiluminescent Assay Kit, #80556; PARP2 Homogeneous Assay Kit, #80702

High Methylated DNA Control, 5 µg at 100 ng/µL

Low Methylated DNA Control 5 µg at 100 ng/µL

Nucleosome Assembly 601 Sequence DNA is a 147 base-pair double-stranded DNA fragment that was identified by Lowary and Widom using the SELEX method [1]. The 601 Sequence DNA has high affinity for histone octamers and is useful for in vitro nucleosome assembly. The DNA contains a 5’ biotin-TEG group.

Nucleosome Assembly 601 Sequence DNA is a 147 base-pair double-stranded DNA fragment that was identified by Lowary and Widom using the SELEX method [1]. The 601 sequence DNA has high affinity for histone octamers and is useful for in vitro nucleosome assembly.