Chemicals & Small Molecules

CHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor that can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β).

Hydrochloride salt of CHIR 99021, a highly selective glycogen synthase kinase-3 (GSK-3) inhibitor that can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β).

Hydrochloride salt of CHIR 99021, a highly selective glycogen synthase kinase-3 (GSK-3) inhibitor that can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β).

CUDC-907 is a dual PI3K and HDAC inhibitor

CUDC-907 is a dual PI3K and HDAC inhibitor

CUDC-907 is a dual PI3K and HDAC inhibitor

Cell-permeable inhibitor of the histone methyltransferase EZH2.

Cell-permeable inhibitor of the histone methyltransferase EZH2.

3-Deazaneplanocin A (DZNep) is an S-Adenosylhomocysteine Hydrolase inhibitor and histone methyltransferase EZH2 inhibitor.