Chemicals & Small Molecules

Guanosine 5'-triphosphate sodium salt hydrate (GTP) functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways.

Guanosine 5'-triphosphate sodium salt hydrate (GTP) functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways.

3-aminobenzamide is a novel, potent inhibitor of PARP. Also acts as a mediator of oxidant-induced myocyte dysfunction during reperfusion.

3-aminobenzamide is a novel, potent inhibitor of PARP. Also acts as a mediator of oxidant-induced myocyte dysfunction during reperfusion.

SiR-NHS ester is the N-hyroxysuccinimidyl ester of SiR. This amine reactive probe enables the preparation of custom SiR probes. SiR-NHS ester can be coupled to any amine bearing ligand: antibody, drug, protein or nucleic acid. SiR is compatible with GFP and/or m-cherry fluorescent proteins. It can be imaged with standard Cy5 filtersets.

SiR-NHS ester is the N-hyroxysuccinimidyl ester of SiR. This amine reactive probe enables the preparation of custom SiR probes. SiR-NHS ester can be coupled to any amine bearing ligand: antibody, drug, protein or nucleic acid. SiR is compatible with GFP and/or m-cherry fluorescent proteins. It can be imaged with standard Cy5 filtersets.

SiR-COOH is the carboxylic acid form of SiR. The free carboxylic acid can be activated with various coupling agents to allow the preparation of custom SiR probes. SiR-COOH can be coupled to a large variety of ligands such as antibodies, drugs, proteins or nucleic acids. SiR is compatible with GFP and/or m-cherry fluorescent proteins. It can be imaged with standard Cy5 filtersets.

SiR-COOH is the carboxylic acid form of SiR. The free carboxylic acid can be activated with various coupling agents to allow the preparation of custom SiR probes. SiR-COOH can be coupled to a large variety of ligands such as antibodies, drugs, proteins or nucleic acids. SiR is compatible with GFP and/or m-cherry fluorescent proteins. It can be imaged with standard Cy5 filtersets.

SiR-tetrazine is a clickable derivative of SiR. This probe reacts with dienophiles such as trans-cyclooctene (TCO) or bicyclononyne (BCN) derivatives, enabling the preparation of custom SiR probes and conjugates. SiR-tetrazine is particularly useful in combination with unnatural amino acid (UAA) incorporation to prepare site selective protein conjugates. SiR-tetrazine is cell permeable and fluorogenic, it can be used to stain live cells as well as fixed ones. SiR is compatible with GFP and/or m-cherry fluorescent proteins. It can be imaged with a standard Cy5 filterset.