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Homovanillic Acid Sulfate (Legacy Tebubio ref. 282TN6685). Homovanillic acid sulfate is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.In psychiatry and neuroscience, brain and cerebrospinal fluid levels of homovanillic acid are measured as a marker of metabolic stress caused by 2-deoxy-D-glucose. Homovanillic acid sulfate presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma.