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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97581 )

      • Imiquimod hydrochloride

        Ref: T22091
        Sizes: 100 mg, 50 mg
        From: DKK285.00

        Imiquimod hydrochloride (Legacy Tebubio ref. 282T22091). Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].

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      • Indomethacin heptyl ester

        Ref: T22092
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK368.00

        Indomethacin heptyl ester (Legacy Tebubio ref. 282T22092). Indomethacin heptyl ester is a non-selective inhibitor of both COX-1 and COX-2

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      • JGB1741

        Ref: T22094
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK465.00

        JGB1741 (Legacy Tebubio ref. 282T22094). JGB1741 (ILS-JGB-1741) is a potent and selective inhibitor of SIRT1 with an IC50 of 15 μM. It modulates the Bax/Bcl2 ratio, cytochrome c release, and PARP cleavage, and increases acetylated p53 levels, leading to p53-mediated apoptosis. JGB1741 can be used in breast cancer studies.

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      • L 012 sodium salt

        Ref: T22096
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK435.00

        L 012 sodium salt (Legacy Tebubio ref. 282T22096). L 012 sodium salt, a luminol analogue, is a widely used chemiluminescent (CL) probe for active oxygen and active nitrogen. L 012 sodium salt is widely used to detect the superoxides (O2•−) derived from NADPH oxidase (Nox) to find Nox inhibitors.

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      • Genipin

        Ref: T2210
        Sizes: 100 mg, 50 mg, 20 mg, 1 mL * 10 mM (in DMSO)
        From: DKK428.00

        Genipin (Legacy Tebubio ref. 282T2210). Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.

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      • ML-031

        Ref: T22101
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg
        From: DKK488.00

        ML-031 (Legacy Tebubio ref. 282T22101). ML-031 activated S1P2 with an EC50 value of 1 μM in an S1P reporter assay.

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      • ML-178

        Ref: T22102
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK360.00

        ML-178 (Legacy Tebubio ref. 282T22102). ML-178, a dichlorobenzene, is a potent and selective agonist of sphingosine-1-phosphate receptor 4 (S1PR4), with an EC50 of 46 nM, and has no effect on other S1P receptors at a concentration of 25 μM.

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      • ML-193

        Ref: T22103
        Sizes: 5 mg, 25 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK338.00

        ML-193 (Legacy Tebubio ref. 282T22103). ML-193 (CID 1261822) is a potent and selective GPR55 antagonist (IC50: 221 nM) with over 27-fold selectivity for GPR55 over GPR35, CB1, and CB2. It can ameliorate motor and sensorimotor deficits in Parkinson’s disease (PD) rats.

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      • ML-291

        Ref: T22104
        Sizes: 2 mg
        From: DKK518.00

        ML-291 (Legacy Tebubio ref. 282T22104). ML291 is a sufonamidebenzamide compound that induces the unfolded protein response (UPR) and overwhelms the adaptive capacity of UPR, resulting in apoptosis in various solid cancer models. It activates the PERK/eIF2a/CHOP apoptotic pathway of UPR and reduces leukemic cell burden [1].

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