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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 89587 )

      • SEW​2871

        Ref: T2171
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK413.00

        SEW​2871 (Legacy Tebubio ref. 282T2171). SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, and inflammation. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.

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      • BAY 41-8543

        Ref: T21712
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg
        From: DKK278.00

        BAY 41-8543 (Legacy Tebubio ref. 282T21712). BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).

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      • BMS453

        Ref: T21714
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK495.00

        BMS453 (Legacy Tebubio ref. 282T21714). BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.

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      • BRD6688

        Ref: T21715
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK840.00

        BRD6688 (Legacy Tebubio ref. 282T21715). BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes

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      • CBHA

        Ref: T21719
        Sizes: 5 mg, 25 mg, 10 mg
        From: DKK1,688.00

        CBHA (Legacy Tebubio ref. 282T21719). m-Carboxycinnamic acid bishydroxamide, an effective HDAC inhibitor, shows ID50 values of 10 nM for HDAC1 and 70 nM for HDAC3 in vitro, demonstrating its potent activity. Additionally, it promotes apoptosis and inhibits tumor growth, highlighting its therapeutic potential [1][2].

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      • SQ22536

        Ref: T2172
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: DKK405.00

        SQ22536 (Legacy Tebubio ref. 282T2172). SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) , the adenosine analogue 9-(Tetrahydro-2-furyl)adenine, inhibited adenylate cyclase activity of crude membrane preparations from catfish (Ictalurus melas) and rat isolated hepatocytes in a non-competitive manner.

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      • GP-82996

        Ref: T21720
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg
        From: DKK360.00

        GP-82996 (Legacy Tebubio ref. 282T21720). GP-82996 (CINK4) is a pharmacological inhibitor specifically targeting CDK4/6, exhibiting IC50 values of 1.5 μM for CDK4/cyclin D1, 5.6 μM for CDK6/cyclin D1, and 25 μM for Cdk5/p35. It effectively induces apoptosis in U2OS cancer cells, positioning it as a potential investigational tool in cancer research [1] [2].

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      • EGF Receptor Peptide Acetate

        Ref: T21723L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK353.00

        EGF Receptor Peptide Acetate (Legacy Tebubio ref. 282T21723L). Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)) exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs to the ErbB family of receptor tyrosine kinases (RTK).

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      • Fas C-Terminal Tripeptide Acetate

        Ref: T21724L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK338.00

        Fas C-Terminal Tripeptide Acetate (Legacy Tebubio ref. 282T21724L). Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.

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