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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97555 )

      • [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate

        Ref: TP1931L1
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg
        From: DKK1,223.00

        [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (Legacy Tebubio ref. 282TP1931L1). [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.

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      • [D-Trp7,9,10]-Substance P

        Ref: TP1932
        Sizes: 1 mg
        Price Enquiry

        [D-Trp7,9,10]-Substance P (Legacy Tebubio ref. 282TP1932). Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.

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      • [D-Trp7,9,10]-Substance P acetate

        Ref: TP1932L1
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg
        From: DKK998.00

        [D-Trp7,9,10]-Substance P acetate (Legacy Tebubio ref. 282TP1932L1). [D-Trp7,9,10]-Substance P acetate is an analogue of substance P which inhibits ion conductance through nicotinic acetylcholine receptors.

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      • R715 TFA(185052-09-9 free base)

        Ref: TP1933
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK1,298.00

        R715 TFA(185052-09-9 free base) (Legacy Tebubio ref. 282TP1933). R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Metabolically stable.

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      • L-R4W2

        Ref: TP1934
        Sizes: 1 mg
        Price Enquiry

        L-R4W2 (Legacy Tebubio ref. 282TP1934). Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.

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      • RAGE antagonist peptide

        Ref: TP1935
        Sizes: 1 mg
        From: DKK2,520.00

        RAGE antagonist peptide (Legacy Tebubio ref. 282TP1935). Receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and RAGE-mediated NF-κB activity in human PDAC cell lines. Inhibits effects of TDI exposure in BALB/c mice.

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      • RAGE antagonist peptide acetate

        Ref: TP1935L1
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK728.00

        RAGE antagonist peptide acetate (Legacy Tebubio ref. 282TP1935L1). RAGE antagonist peptide acetate is an advanced antagonist of glycation end products (RAGE). RAGE antagonist peptide acetate possesses anti-tumor and anti-inflammatory activities. RAGE antagonist peptide acetate prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4.

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      • RFRP-3(human)

        Ref: TP1936
        Sizes: 1 mg
        From: DKK4,193.00

        RFRP-3(human) (Legacy Tebubio ref. 282TP1936). Agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons.

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      • RFRP3(human) acetate(311309-27-0 free base)

        Ref: TP1936L1
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg
        From: DKK683.00

        RFRP3(human) acetate(311309-27-0 free base) (Legacy Tebubio ref. 282TP1936L1). RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM.

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