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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97553 )

      • pep2-EVKI acetate(1315378-67-6 free base)

        Ref: TP1943L1
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK1,418.00

        pep2-EVKI acetate(1315378-67-6 free base) (Legacy Tebubio ref. 282TP1943L1). Pep2-EVKI acetate is a cell-permeable peptide. Pep2-EVKI acetate interferes the interaction between protein interacting with C-kinase (PICK1) and GluR2 AMPA receptor subunits.

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      • pep2-SVKI

        Ref: TP1944
        Sizes: 2 mg
        Price Enquiry

        pep2-SVKI (Legacy Tebubio ref. 282TP1944). Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1). Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD).

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      • pep2-SVKI acetate

        Ref: TP1944L1
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK1,133.00

        pep2-SVKI acetate (Legacy Tebubio ref. 282TP1944L1). Pep2-SVKI acetate(pep2-SVKI acetate (328944-75-8 free base)) is a synthetic peptide salt that prevents internalization of AMPA-type glutamate receptor.

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      • Pep2m, myristoylated

        Ref: TP1945
        Sizes: 1 mg
        Price Enquiry

        Pep2m, myristoylated (Legacy Tebubio ref. 282TP1945). Cell-permeable, myristoylated form of pep2m. Peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF), a protein that regulates AMPA receptor function. Reduces postsynaptic currents in CA1 neurons, AMPA-mediated currents in cultured hippocampal neurons and AMPA receptor surface expression.

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      • Pep2m, myristoylated acetate

        Ref: TP1945L1
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg
        From: DKK810.00

        Pep2m, myristoylated acetate (Legacy Tebubio ref. 282TP1945L1). Pep2m, myristoylated acetate is a Cell-permeable, myristoylated form of pep2m. Peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF), a protein that regulates AMPA receptor function. Reduces postsynaptic currents in CA1 neurons, AMPA-mediated currents in cultured hippocampal neurons and AMPA receptor surface expression.

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      • QWF

        Ref: TP1946
        Sizes: 5 mg
        From: DKK4,500.00

        QWF (Legacy Tebubio ref. 282TP1946). Tripeptide substance P (SP) antagonist (IC50 = 90 μM). Also inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Inhibits SP-induced IgE-independent degranulation of mast cells in vitro. Inhibits compound 48/80-induced MRGPRX2 activation and scratching in mice in vivo.

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      • P110

        Ref: TP1947
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 10 mg
        Price Enquiry

        P110 (Legacy Tebubio ref. 282TP1947). Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen species (ROS) production in vitro. Reduces programmed cell death and improves cell viability by protecting mitochondrial integrity. Reduces mitochondrial fragmentation and mitochondrial ROS production in mouse model of Parkinson's disease. Cell permeable.

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      • P110 TFA

        Ref: TP1947L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK300.00

        P110 TFA (Legacy Tebubio ref. 282TP1947L). P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity.

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      • PBP10

        Ref: TP1948
        Sizes: 1 mg
        Price Enquiry

        PBP10 (Legacy Tebubio ref. 282TP1948). Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.

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