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    Results for Chemicals & Small Molecules ( 97555 )

      • Ref: TP1973L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK2,498.00

        OXA (17-33) acetate (Legacy Tebubio ref. 282TP1973L). OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).

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      • Ref: TP1974
        Sizes: 1 mg

        Obtustatin (Legacy Tebubio ref. 282TP1974). Highly potent integrin α1β1 inhibitor (IC50 = 0.8 nM for α1β1 binding to type IV collagen). Selective for α1β1 over α2β1, αIIbβ3, αvβ3, α4β1, α5β6, α9β1 and α4β7. Inhibits FGF2-stimulated angiogenesis in the chicken chorioallantoic model. Displays antitumor efficacy in a synergistic mouse model of Lewis lung carcinoma; blocks human melanoma growth in nude mice.

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      • Ref: TP1975
        Sizes: 1 mg
        From: DKK10,050.00

        [Ala11,D-Leu15]-Orexin B(human) (Legacy Tebubio ref. 282TP1975). Highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.

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      • Ref: TP1975L
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg
        From: DKK4,463.00

        [Ala11,D-Leu15]-Orexin B acetate (Legacy Tebubio ref. 282TP1975L). [Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).

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      • Ref: TP1976
        Sizes: 1 mg
        From: DKK9,113.00

        Oxyntomodulin (Legacy Tebubio ref. 282TP1976). GLP-1 receptor agonist. Endogenous preproglucagon-derived neuropeptide that modulates feeding and metabolism. Also secreted by intestinal L-cells. Increases cAMP production and inhibits gastric acid secretion in rat stomach. Also weak glucagon receptor agonist.

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      • Ref: TP1976L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK1,575.00

        Oxyntomodulin acetate (Legacy Tebubio ref. 282TP1976L). Oxyntomodulin acetate, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist[1].

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      • Ref: TP1977
        Sizes: 10 mg

        187-1, N-WASP inhibitor (Legacy Tebubio ref. 282TP1977). Inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by stabilizing the autoinhibited state of the protein. Blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly (IC50 ~ 2 μM) but does not directly inhibit actin polymerization.

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      • Ref: TP1978
        Sizes: 1 mg
        From: DKK7,965.00

        11R-VIVIT (Legacy Tebubio ref. 282TP1978). NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. Cell permeable.

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      • Ref: TP1978L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK503.00

        NFAT inhibitor, Cell Permeable aceate (Legacy Tebubio ref. 282TP1978L). NFAT inhibitor, Cell Permeable aceate is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. It can be used for the research of podocyte and diabetic nephropathy.

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