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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97555 )

      • CLK-IN-T3

        Ref: T14980
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg
        From: DKK458.00

        CLK-IN-T3 (Legacy Tebubio ref. 282T14980). CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.

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      • Clobetasone butyrate

        Ref: T14981
        Sizes: 25 mg, 100 mg, 50 mg, 500 mg, 1 mL * 10 mM (in DMSO)
        From: DKK315.00

        Clobetasone butyrate (Legacy Tebubio ref. 282T14981). Clobetasone butyrate, a synthetic glucocorticoid with topical anti-inflammatory activity, is effective in treating corticosteroid-responsive dermatoses, such as atopic dermatitis and psoriasis, especially within skin tissues.

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      • Clofilium tosylate

        Ref: T14982
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK263.00

        Clofilium tosylate (Legacy Tebubio ref. 282T14982). Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.

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      • Clomethiazole

        Ref: T14983
        Sizes: 100 mg, 500 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: DKK353.00

        Clomethiazole (Legacy Tebubio ref. 282T14983). Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes.

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      • CLP257

        Ref: T14984
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg
        From: DKK330.00

        CLP257 (Legacy Tebubio ref. 282T14984). CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 alleviates hypersensitivity in rats with neuropathic painc and it also modulates plasmalemmal KCC2 protein turnover post-translationally. CLP257 restores impaired Cl− transport in neurons with diminished KCC2 activity.

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      • CMP8

        Ref: T14987
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: DKK1,298.00

        CMP8 (Legacy Tebubio ref. 282T14987). CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, respectively.

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      • CMPD1

        Ref: T14988
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK270.00

        CMPD1 (Legacy Tebubio ref. 282T14988). CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM).

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      • CMPD101

        Ref: T14989
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK518.00

        CMPD101 (Legacy Tebubio ref. 282T14989). CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with IC50s of 3.1 μM , 2.3 μM, 1.4 μM and 8.1 μM, respectively.

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      • Dutasteride

        Ref: T1499
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: DKK278.00

        Dutasteride (Legacy Tebubio ref. 282T1499). Dutasteride (GI 198745) is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.

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